Stocks · Healthcare · Biotechnology
Annovis Bio, Inc. ANVS
$1.18 +0.85% Close, Oct 2, 2026 · NYSE · Market cap $50.2M
Weak trendExpensive vs sectorHigh risk
Next earnings report: Nov 11, 2026
Scroll or pinch to zoom, drag to move. Daily prices adjusted for splits. Markers: E = earnings (green beat, red miss), S = split, D = dividend.
Three things to know
- The diluted share count rose 92.5% in a year.
- The stock is 77% below its highest close of the past year.
- The stock is in a downtrend: below its 200-day average, with the 50-day average below the 200-day.
PromtFinance scores
Each score is a percentile within the Healthcare sector (0–100). Under each score: how the stock ranks in its sector on every component. As of Oct 5, 2026.
How fast revenue, earnings and cash flow are growing.
Returns on capital, margins, earnings quality and balance-sheet strength.
- Return on invested capitalBottom 2%
- Accruals (lower is better)Top 8%
- Interest coverBottom 21%
How cheap the shares are relative to earnings, cash flow and their own history.
- Earnings yieldBottom 3%
- Free-cash-flow yieldBottom 4%
- EBITDA / enterprise valueBottom 3%
Strength and persistence of the price trend, including versus the S&P 500.
- 12-month return excluding last monthBottom 22%
- 6-month returnBottom 5%
- 1-year return vs S&P 500Bottom 13%
- Distance from 52-week highBottom 4%
- Trend checklist (0–4)Bottom 14%
Earnings surprises and analyst sentiment (estimate-revision history is being collected).
- Average EPS surprise, last 4 quartersBottom 21%
- Consecutive EPS beatsBottom 49%
- Share of analysts rating BuyTop 49%
- Upside to consensus price targetTop 1%
Low volatility, shallow drawdowns, low market sensitivity and modest leverage.
- Volatility, 60 days (lower is better)Bottom 24%
- Maximum drawdown, 3 yearsBottom 6%
- Beta vs S&P 500 (lower is better)Bottom 8%
Fundamental momentum
| Measure | Now (TTM) | Year / quarter before | Sector rank | |
|---|---|---|---|---|
| Return on invested capital | -400.4% | — | Bottom 2% |
Quality of earnings and balance sheet
- Accruals (net income − OCF) / assetsLower is better; high accruals can signal weaker earnings quality.
- -28.1%
- Net debt / EBITDABelow 1× is conservative; above 3× is high leverage.
- Net cash
- Interest cover (operating income / interest)How many times operating profit covers interest.
- -31.2×
Shareholder returns
- Dividend yield (dividends paid, TTM)
- 0.00%
- Net buyback yield (TTM)
- -89.52%
- Shareholder yield
- -89.52%
- Share count change, 1 year
- +92.5%
- Share count change, 3-year CAGR
- +61.2%
Shareholder yield = dividends + net buybacks over the last four quarters, divided by market cap.
Based on the four quarters through Jun 30, 2026 (filed Aug 14, 2026).
Earnings and expectations
Earnings momentum
- Consecutive EPS beats
- 1
- Beats in the last 8 reports
- 3 of 8
- Average EPS surprise, last 4
- -19.2%
- Average 2-day reaction, last 8
- +3.4%
- Positive 20 days after report
- 2 of 8
Analysts
- Consensus price target
- $25.67
- Target vs current price
- +2075.4%
- Analysts with a rating
- 9
- Share rating Buy or Strong Buy
- 78%
- Consensus rating
- Buy
How the stock reacted to recent reports
| Report date | EPS surprise | 2 days | 5 days | 20 days | 60 days |
|---|---|---|---|---|---|
| Aug 14, 2026 | +11.8% | +3.4% | +0.0% | -37.4% | — |
| May 15, 2026 | -59.5% | -3.3% | +0.9% | -16.4% | -11.3% |
| Mar 16, 2026 | -26.5% | +12.3% | +3.2% | -34.1% | -29.8% |
| Nov 12, 2025 | -2.8% | +15.2% | +59.7% | +99.1% | +18.0% |
| Aug 12, 2025 | +11.1% | -1.8% | -4.6% | -16.3% | -33.0% |
| May 13, 2025 | +31.9% | +9.7% | +36.8% | +85.8% | +67.7% |
| Mar 21, 2025 | -13.2% | -2.8% | +2.8% | -32.2% | +57.2% |
| Nov 8, 2024 | -83.0% | -5.2% | -19.0% | -30.3% | -64.2% |
Returns from the close before each report. Past reactions do not determine future ones.
Earnings history
| Report date | EPS | Estimate | Surprise | Revenue |
|---|---|---|---|---|
| Aug 14, 2026 | -$0.40 | -$0.45 | +11.8% | — |
| May 15, 2026 | -$0.63 | -$0.40 | -59.5% | — |
| Mar 16, 2026 | -$0.39 | -$0.31 | -26.5% | — |
| Nov 12, 2025 | -$0.37 | -$0.36 | -2.8% | — |
| Aug 12, 2025 | -$0.32 | -$0.36 | +11.1% | — |
| May 13, 2025 | -$0.32 | -$0.47 | +31.9% | — |
| Mar 21, 2025 | -$0.43 | -$0.38 | -13.2% | — |
| Nov 8, 2024 | -$0.97 | -$0.53 | -83.0% | — |
Valuation in context
| Multiple | Now | 5-year median | 5-year percentile | Sector rank (cheapness) |
|---|---|---|---|---|
| Free-cash-flow yield | -86.34% | — | — | Bottom 4% |
| Earnings yield | -151.69% | — | — | Bottom 3% |
Technical state
Trend checklist
- ✗ Price above 20-day average
- ✗ Price above 50-day average
- ✗ Price above 200-day average
- ✗ 50-day average above 200-day
- ✓ MACD histogram positive
Trend quality
- Days above the 50-day average
- 0
- Days above the 200-day average
- 0
- 50-day average slope (20 days)
- -13.3%
- 200-day average slope (20 days)
- -12.0%
- Distance from 50-day average
- -23.8%
- Distance from 200-day average
- -45.7%
- RSI (14)
- 37.9
- Relative volume
- 0.43×
Risk and drawdowns
- Volatility, 60 days (annualized)
- 73.2%
- Volatility vs own 5-year history
- 23th percentile · Normal for this stock
- Beta vs S&P 500 (2 years, weekly)
- 2.25
- Correlation with S&P 500
- 0.33
- Current drawdown from 1-year high
- -76.9%
- Maximum drawdown, 3 years
- -94.7%
Largest declines in the past six years
| From peak | To low | Decline | Length | Recovery |
|---|---|---|---|---|
| Jul 13, 2021 | Sep 16, 2026 | -99.1% | 1300 days | Not yet recovered |
| Mar 17, 2021 | Apr 16, 2021 | -43.9% | 21 days | 25 days (May 21, 2021) |
| May 21, 2021 | May 27, 2021 | -25.7% | 4 days | 4 days (Jun 3, 2021) |
| Feb 22, 2021 | Mar 5, 2021 | -25.1% | 9 days | 6 days (Mar 15, 2021) |
| Oct 8, 2020 | Nov 2, 2020 | -24.7% | 17 days | 18 days (Nov 27, 2020) |
Declines of 10% or more from a closing high, measured on daily closes.
Financial statements
- Market cap
- $50.2M
- EPS, diluted (TTM)
- -$1.79
- Revenue (TTM)
- $0
- 52-week range
- $1.04 – $5.50
| FY 2021 | FY 2022 | FY 2023 | FY 2024 | FY 2025 | |
|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 |
| Gross profit | $0 | $0 | $0 | $0 | $0 |
| Operating income | -$14.5M | -$25.5M | -$45.0M | -$26.7M | -$29.7M |
| Net income | -$14.5M | -$25.3M | -$56.2M | -$24.6M | -$28.9M |
| EPS (diluted) | -$1.90 | -$3.10 | -$6.23 | -$2.31 | -$1.40 |
| Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 | Q1 2026 | Q2 2026 | |
|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Net income | -$12.6M | -$5.9M | -$5.5M | -$6.2M | -$7.3M | -$9.8M | -$17.6M | -$14.8M |
| EPS (diluted) | -$0.97 | -$0.48 | -$0.32 | -$0.32 | -$0.37 | -$0.40 | -$0.63 | -$0.39 |
| FY 2021 | FY 2022 | FY 2023 | FY 2024 | FY 2025 | |
|---|---|---|---|---|---|
| Operating cash flow | -$9.1M | -$17.3M | -$40.0M | -$21.9M | -$25.6M |
| Capital expenditure | $0 | $0 | $0 | $0 | $0 |
| Free cash flow | -$9.1M | -$17.3M | -$40.0M | -$21.9M | -$25.6M |
| Dividends paid | $0 | $0 | $0 | $0 | $0 |
| Net share buybacks | $46.6M | $4,613 | $16.9M | $26.7M | $34.6M |
Cash outflows are shown as negative numbers.
- Cash and short-term investments
- $18.7M
- Total assets
- $22.0M
- Total liabilities
- $26.3M
- Total debt
- $0
- Net debt
- -$18.7M
- Shareholders’ equity
- -$4.3M
As of Jun 30, 2026 (filed Aug 14, 2026).
Short interest
- Shares sold short
- 6,022,040
- Days to cover
- 3.19
- Change vs previous report
- +20.7%
FINRA short interest, settlement date Sep 15, 2026.