Stocks · Healthcare · Biotechnology
Assembly Biosciences, Inc. ASMB
$22.54 -1.91% Close, Oct 2, 2026 · NASDAQ · Market cap $446.7M
Strong growth
Next earnings report: Nov 9, 2026
Scroll or pinch to zoom, drag to move. Daily prices adjusted for splits. Markers: E = earnings (green beat, red miss), S = split, D = dividend.
Three things to know
- Revenue over the last four quarters was $74.8M, up 125.1% from a year earlier, accelerating from 121.1% a quarter earlier.
- Operating margin widened to -11.8% from -130.9% a year earlier.
- The diluted share count rose 146.3% in a year.
PromtFinance scores
Each score is a percentile within the Healthcare sector (0–100). Under each score: how the stock ranks in its sector on every component. As of Oct 5, 2026.
How fast revenue, earnings and cash flow are growing.
- Revenue growth (TTM, YoY)Top 9%
- Revenue growth accelerationTop 20%
Returns on capital, margins, earnings quality and balance-sheet strength.
- Return on invested capitalTop 35%
- Gross marginTop 34%
- Operating marginBottom 47%
- Accruals (lower is better)Bottom 6%
- Net debt / EBITDA (lower is better)Top 1%
How cheap the shares are relative to earnings, cash flow and their own history.
- Earnings yieldTop 22%
- Free-cash-flow yieldBottom 40%
- EBITDA / enterprise valueTop 38%
- Sales / enterprise valueBottom 45%
Strength and persistence of the price trend, including versus the S&P 500.
- 12-month return excluding last monthTop 34%
- 6-month returnBottom 22%
- 1-year return vs S&P 500Bottom 37%
- Distance from 52-week highBottom 37%
- Trend checklist (0–4)Bottom 38%
Earnings surprises and analyst sentiment (estimate-revision history is being collected).
- Average EPS surprise, last 4 quartersTop 4%
- Consecutive EPS beatsTop 25%
- Share of analysts rating BuyBottom 20%
- Upside to consensus price targetTop 31%
Low volatility, shallow drawdowns, low market sensitivity and modest leverage.
- Volatility, 60 days (lower is better)Bottom 39%
- Maximum drawdown, 3 yearsTop 31%
- Beta vs S&P 500 (lower is better)Bottom 36%
- Net debt / EBITDA (lower is better)Top 1%
What changed
Latest four quarters versus the same period a year earlier (growth: versus one quarter earlier).
| Measure | Before | Now | |
|---|---|---|---|
| Revenue growth (YoY) | 121.1% | 125.1% | ↑ |
| Gross margin | -76.8% | 77.7% | ↑ |
| Operating margin | -130.9% | -11.8% | ↑ |
| FCF margin | -168.0% | -51.5% | ↑ |
Fundamental momentum
| Measure | Now (TTM) | Year / quarter before | Sector rank | |
|---|---|---|---|---|
| Revenue growth (TTM, YoY) | 125.1% | 121.1% | ↑ | Top 9% |
| Gross margin | 77.7% | -76.8% | ↑ | Top 34% |
| Operating margin | -11.8% | -130.9% | ↑ | Bottom 47% |
| Net margin | -0.1% | -117.2% | ↑ | — |
| Free-cash-flow margin | -51.5% | -168.0% | ↑ | — |
| Return on invested capital | -2.9% | — | Top 35% |
Quality of earnings and balance sheet
- Accruals (net income − OCF) / assetsLower is better; high accruals can signal weaker earnings quality.
- 11.6%
- Stock-based compensation / revenueA cost to shareholders through dilution.
- 8.9%
- Receivables growth vs revenue growthReceivables growing much faster than sales can be a warning.
- +48.9 pp
- Net debt / EBITDABelow 1× is conservative; above 3× is high leverage.
- -440.24×
Shareholder returns
- Dividend yield (dividends paid, TTM)
- 0.00%
- Net buyback yield (TTM)
- -62.97%
- Shareholder yield
- -62.97%
- Share count change, 1 year
- +146.3%
- Share count change, 3-year CAGR
- +63.0%
Shareholder yield = dividends + net buybacks over the last four quarters, divided by market cap.
Based on the four quarters through Jun 30, 2026 (filed Aug 13, 2026).
Earnings and expectations
Earnings momentum
- Consecutive EPS beats
- 3
- Beats in the last 8 reports
- 6 of 8
- Average EPS surprise, last 4
- +100.0%
- Average 2-day reaction, last 8
- +1.6%
- Positive 20 days after report
- 5 of 8
Analysts
- Consensus price target
- $51.67
- Target vs current price
- +129.2%
- Analysts with a rating
- 11
- Share rating Buy or Strong Buy
- 55%
- Consensus rating
- Buy
How the stock reacted to recent reports
| Report date | EPS surprise | 2 days | 5 days | 20 days | 60 days |
|---|---|---|---|---|---|
| Aug 13, 2026 | +72.4% | +10.7% | +25.1% | +12.6% | — |
| May 7, 2026 | +26.0% | -1.4% | +1.1% | -23.1% | -19.1% |
| Mar 19, 2026 | +586.3% | -0.0% | +4.2% | +6.5% | -16.6% |
| Nov 10, 2025 | -44.0% | +2.8% | +17.7% | +13.4% | -18.6% |
| Aug 6, 2025 | -103.6% | +3.0% | +27.2% | +26.7% | +64.3% |
| May 8, 2025 | +41.8% | -6.0% | -2.4% | +27.4% | +56.3% |
| Mar 20, 2025 | +10.3% | -1.5% | -0.4% | -7.7% | +55.3% |
| Nov 7, 2024 | +25.2% | +5.1% | +0.3% | -2.0% | -14.7% |
Returns from the close before each report. Past reactions do not determine future ones.
Earnings history
| Report date | EPS | Estimate | Surprise | Revenue |
|---|---|---|---|---|
| Aug 13, 2026 | -$0.20 | -$0.72 | +72.4% | $13.4M |
| May 7, 2026 | -$0.54 | -$0.73 | +26.0% | $8.2M |
| Mar 19, 2026 | $2.48 | -$0.51 | +586.3% | $42.5M |
| Nov 10, 2025 | -$0.72 | -$0.50 | -44.0% | $10.8M |
| Aug 6, 2025 | -$1.33 | -$0.65 | -103.6% | $9.6M |
| May 8, 2025 | -$1.17 | -$2.01 | +41.8% | $9.4M |
| Mar 20, 2025 | -$1.57 | -$1.75 | +10.3% | $7.4M |
| Nov 7, 2024 | -$1.51 | -$2.02 | +25.2% | $6.8M |
Valuation in context
| Multiple | Now | 5-year median | 5-year percentile | Sector rank (cheapness) |
|---|---|---|---|---|
| P/E (trailing) | 41.0× | — | — | Top 22% |
| EV / EBITDA | 6128.6× | — | — | Top 38% |
| EV / Sales | 5.57× | — | — | Bottom 45% |
| Free-cash-flow yield | -8.63% | — | — | Bottom 40% |
| Earnings yield | 2.44% | — | — | Top 22% |
Technical state
Trend checklist
- ✗ Price above 20-day average
- ✗ Price above 50-day average
- ✗ Price above 200-day average
- ✓ 50-day average above 200-day
- ✗ MACD histogram positive
Trend quality
- Days above the 50-day average
- 0
- Days above the 200-day average
- 0
- 50-day average slope (20 days)
- -0.2%
- 200-day average slope (20 days)
- -3.2%
- Distance from 50-day average
- -21.9%
- Distance from 200-day average
- -20.5%
- RSI (14)
- 25.2
- Relative volume
- 0.95×
Risk and drawdowns
- Volatility, 60 days (annualized)
- 61.8%
- Volatility vs own 5-year history
- 58th percentile · Normal for this stock
- Beta vs S&P 500 (2 years, weekly)
- 1.40
- Correlation with S&P 500
- 0.33
- Current drawdown from 1-year high
- -41.5%
- Maximum drawdown, 3 years
- -57.5%
Largest declines in the past six years
| From peak | To low | Decline | Length | Recovery |
|---|---|---|---|---|
| Oct 1, 2020 | Nov 21, 2023 | -96.2% | 790 days | Not yet recovered |
Declines of 10% or more from a closing high, measured on daily closes.
Financial statements
- Market cap
- $446.7M
- P/E (TTM)
- 41.0
- EPS, diluted (TTM)
- $0.55
- Revenue (TTM)
- $74.8M
- 52-week range
- $21.80 – $39.71
| FY 2021 | FY 2022 | FY 2023 | FY 2024 | FY 2025 | |
|---|---|---|---|---|---|
| Revenue | $6.3M | $0 | $7.2M | $28.5M | $72.3M |
| Gross profit | $6.3M | -$69.1M | -$41.7M | -$27.4M | $72.2M |
| Operating income | -$132.7M | -$94.1M | -$64.6M | -$45.4M | -$12.1M |
| Net income | -$129.9M | -$93.1M | -$61.2M | -$40.2M | -$6.1M |
| EPS (diluted) | -$36.00 | -$22.82 | -$13.38 | -$6.69 | -$0.55 |
| Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 | Q1 2026 | Q2 2026 | |
|---|---|---|---|---|---|---|---|---|
| Revenue | $6.8M | $7.4M | $9.4M | $9.6M | $10.8M | $42.5M | $8.2M | $13.4M |
| Net income | -$9.6M | -$10.3M | -$8.8M | -$10.2M | -$9.2M | $22.1M | -$9.1M | -$3.9M |
| EPS (diluted) | -$1.51 | -$1.72 | -$1.17 | -$1.33 | -$1.20 | $2.49 | -$0.54 | -$0.20 |
| FY 2021 | FY 2022 | FY 2023 | FY 2024 | FY 2025 | |
|---|---|---|---|---|---|
| Operating cash flow | -$93.4M | -$84.5M | $22.7M | -$51.1M | -$41.1M |
| Capital expenditure | -$3.1M | -$102,000 | -$255,000 | -$28,000 | -$66,000 |
| Free cash flow | -$96.5M | -$84.6M | $22.5M | -$51.1M | -$41.2M |
| Dividends paid | $0 | $0 | $0 | $0 | $0 |
| Net share buybacks | $52.8M | $325,000 | $13.7M | $29.3M | $174.7M |
Cash outflows are shown as negative numbers.
- Cash and short-term investments
- $320.4M
- Total assets
- $330.8M
- Total liabilities
- $25.2M
- Total debt
- $2.4M
- Net debt
- -$29.9M
- Shareholders’ equity
- $305.6M
As of Jun 30, 2026 (filed Aug 13, 2026).
Short interest
- Shares sold short
- 2,095,568
- Days to cover
- 6.26
- Change vs previous report
- -1.2%
FINRA short interest, settlement date Sep 15, 2026.
Stock splits
- Feb 12, 2024
- 1-for-12
- Jul 14, 2014
- 1-for-5