Stocks · Healthcare · Biotechnology

Definium Therapeutics, Inc. DFTX

$37.40 -0.53% Close, Oct 2, 2026 · NASDAQ · Market cap $4.96B

Strong trend

Next earnings report: Nov 5, 2026

Scroll or pinch to zoom, drag to move. Daily prices adjusted for splits. Markers: E = earnings (green beat, red miss), S = split, D = dividend.

Three things to know

  1. The diluted share count rose 29.7% in a year.
  2. Over the past year the stock returned +203.3%, ahead of the S&P 500 by 188.3 percentage points.
  3. The stock is in an uptrend: above its 200-day average for 316 trading days, with the 50-day average above the 200-day.

PromtFinance scores

Each score is a percentile within the Healthcare sector (0–100). Under each score: how the stock ranks in its sector on every component. As of Oct 5, 2026.

Growth—Not enough data

How fast revenue, earnings and cash flow are growing.

Quality65Positive

Returns on capital, margins, earnings quality and balance-sheet strength.

  • Return on invested capitalBottom 48%
  • Accruals (lower is better)Top 19%
  • Interest coverBottom 30%
Value49Neutral

How cheap the shares are relative to earnings, cash flow and their own history.

  • Earnings yieldBottom 47%
  • Free-cash-flow yieldTop 47%
  • EBITDA / enterprise valueBottom 43%
Momentum88Strong

Strength and persistence of the price trend, including versus the S&P 500.

  • 12-month return excluding last monthTop 6%
  • 6-month returnTop 12%
  • 1-year return vs S&P 500Top 5%
  • Distance from 52-week highTop 39%
  • Trend checklist (0–4)Top 39%
Revisions34Weak

Earnings surprises and analyst sentiment (estimate-revision history is being collected).

  • Average EPS surprise, last 4 quartersBottom 12%
  • Consecutive EPS beatsBottom 20%
  • Share of analysts rating BuyTop 10%
  • Upside to consensus price targetTop 43%
Stability52Neutral

Low volatility, shallow drawdowns, low market sensitivity and modest leverage.

  • Volatility, 60 days (lower is better)Bottom 49%
  • Maximum drawdown, 3 yearsTop 33%
  • Beta vs S&P 500 (lower is better)Bottom 31%

Fundamental momentum

MeasureNow (TTM)Year / quarter beforeSector rank
Return on invested capital-23.8%—Bottom 48%

Quality of earnings and balance sheet

Accruals (net income − OCF) / assetsLower is better; high accruals can signal weaker earnings quality.
-16.8%
Net debt / EBITDABelow 1× is conservative; above 3× is high leverage.
Net cash
Interest cover (operating income / interest)How many times operating profit covers interest.
-16.9×

Shareholder returns

Dividend yield (dividends paid, TTM)
0.00%
Net buyback yield (TTM)
-21.37%
Shareholder yield
-21.37%
Share count change, 1 year
+29.7%
Share count change, 3-year CAGR
+42.1%

Shareholder yield = dividends + net buybacks over the last four quarters, divided by market cap.

Based on the four quarters through Jun 30, 2026 (filed Aug 6, 2026).

Earnings and expectations

Earnings momentum

Consecutive EPS beats
0
Beats in the last 8 reports
2 of 8
Average EPS surprise, last 4
-68.2%
Average 2-day reaction, last 8
+1.6%
Positive 20 days after report
6 of 8

Analysts

Consensus price target
$67.45
Target vs current price
+80.3%
Analysts with a rating
12
Share rating Buy or Strong Buy
100%
Consensus rating
Buy

How the stock reacted to recent reports

Report dateEPS surprise2 days5 days20 days60 days
Aug 6, 2026-166.2%+3.9%-3.6%-12.4%—
May 7, 2026-51.1%-0.9%-6.0%+5.0%+78.4%
Feb 26, 2026-5.4%-1.9%+0.8%+4.8%+28.5%
Nov 6, 2025-50.0%-1.6%+5.3%+7.8%+55.2%
Jul 31, 2025-31.6%+0.7%+9.5%+9.1%+38.1%
May 8, 2025+2.8%-2.0%-0.8%+16.7%+42.0%
Mar 6, 2025-24.2%+3.6%+1.1%-6.4%+13.8%
Nov 7, 2024+3.6%+11.4%+24.4%+5.3%+38.4%

Returns from the close before each report. Past reactions do not determine future ones.

Earnings history

Report dateEPSEstimateSurpriseRevenue
Aug 6, 2026-$1.44-$0.54-166.2%—
May 7, 2026-$0.71-$0.47-51.1%—
Feb 26, 2026-$0.51-$0.48-5.4%—
Nov 6, 2025-$0.78-$0.52-50.0%—
Jul 31, 2025-$0.50-$0.38-31.6%—
May 8, 2025-$0.35-$0.36+2.8%—
Mar 6, 2025-$0.41-$0.33-24.2%—
Nov 7, 2024-$0.27-$0.28+3.6%—

Valuation in context

MultipleNow5-year median5-year percentileSector rank (cheapness)
Free-cash-flow yield-3.36%——Top 47%
Earnings yield-9.17%——Bottom 47%

Technical state

Trend checklist

  • ✗ Price above 20-day average
  • ✗ Price above 50-day average
  • ✓ Price above 200-day average
  • ✓ 50-day average above 200-day
  • ✓ MACD histogram positive

Trend quality

Days above the 50-day average
0
Days above the 200-day average
316
50-day average slope (20 days)
-6.2%
200-day average slope (20 days)
+10.6%
Distance from 50-day average
-9.1%
Distance from 200-day average
+36.4%
RSI (14)
43.5
Relative volume
0.66×

Risk and drawdowns

Volatility, 60 days (annualized)
56.1%
Volatility vs own 5-year history
10th percentile · Low for this stock
Beta vs S&P 500 (2 years, weekly)
1.48
Correlation with S&P 500
0.25
Current drawdown from 1-year high
-22.8%
Maximum drawdown, 3 years
-58.4%

Largest declines in the past six years

From peakTo lowDeclineLengthRecovery
Apr 26, 2021Dec 28, 2022-97.0%423 daysNot yet recovered
Dec 14, 2020Apr 22, 2021-51.3%88 days2 days (Apr 26, 2021)
Oct 19, 2020Oct 30, 2020-26.0%9 days11 days (Nov 16, 2020)
Sep 25, 2020Sep 30, 2020-14.9%3 days5 days (Oct 7, 2020)
Oct 8, 2020Oct 14, 2020-11.6%4 days3 days (Oct 19, 2020)

Declines of 10% or more from a closing high, measured on daily closes.

Financial statements

Market cap
$4.96B
EPS, diluted (TTM)
-$3.43
Revenue (TTM)
$0
52-week range
$10.46 – $49.70
FY 2021FY 2022FY 2023FY 2024FY 2025
Revenue$0$0$0$0$0
Gross profit$0$0-$3.2M-$527,000$0
Operating income-$93.9M-$66.3M-$93.9M-$103.9M-$166.3M
Net income-$93.0M-$56.8M-$95.7M-$108.7M-$183.8M
EPS (diluted)-$3.40-$1.53-$2.44-$0.15-$2.06
Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
Revenue$0$0$0$0$0$0$0$0
Net income-$13.7M-$34.7M-$23.3M-$42.7M-$67.3M-$50.4M-$77.1M-$159.0M
EPS (diluted)-$0.17-$0.41-$0.35-$0.50-$0.78-$0.50-$0.71-$1.44
FY 2021FY 2022FY 2023FY 2024FY 2025
Operating cash flow-$45.8M-$50.1M-$64.4M-$79.1M-$131.6M
Capital expenditure$0$0$0$0$0
Free cash flow-$45.8M-$50.1M-$64.4M-$79.1M-$131.6M
Dividends paid$0$0$0$0$0
Net share buybacks$81.9M$42.3M$7.5M$250.0M$259.9M

Cash outflows are shown as negative numbers.

Cash and short-term investments
$1.08B
Total assets
$1.11B
Total liabilities
$194.2M
Total debt
$36.5M
Net debt
-$618.8M
Shareholders’ equity
$918.7M

As of Jun 30, 2026 (filed Aug 6, 2026).

Short interest

Shares sold short
11,785,195
Days to cover
5.19
Change vs previous report
+19.8%

FINRA short interest, settlement date Sep 15, 2026.

Stock splits

Aug 29, 2022
1-for-15
Mar 3, 2020
1-for-8