Stocks · Healthcare · Biotechnology

Maze Therapeutics, Inc. MAZE

$26.43 -0.83% Close, Oct 2, 2026 · NASDAQ · Market cap $1.46B

Strong growth

Next earnings report: Nov 5, 2026

Scroll or pinch to zoom, drag to move. Daily prices adjusted for splits. Markers: E = earnings (green beat, red miss), S = split, D = dividend.

Three things to know

  1. Revenue over the last four quarters was $20.0M, up 700.0% from a year earlier, accelerating from -88.1% a quarter earlier.
  2. Operating margin widened to -728.1% from -5033.2% a year earlier.
  3. The diluted share count rose 34.5% in a year.

PromtFinance scores

Each score is a percentile within the Healthcare sector (0–100). Under each score: how the stock ranks in its sector on every component. As of Oct 5, 2026.

Growth99Exceptional

How fast revenue, earnings and cash flow are growing.

  • Revenue growth (TTM, YoY)Top 4%
  • Revenue growth accelerationTop 2%
Quality29Very weak

Returns on capital, margins, earnings quality and balance-sheet strength.

  • Return on invested capitalBottom 43%
  • Gross marginTop 13%
  • Operating marginBottom 14%
  • Accruals (lower is better)Bottom 43%
  • Interest coverBottom 14%
Value33Weak

How cheap the shares are relative to earnings, cash flow and their own history.

  • Earnings yieldBottom 45%
  • Free-cash-flow yieldBottom 43%
  • EBITDA / enterprise valueBottom 39%
  • Sales / enterprise valueBottom 11%
Momentum32Weak

Strength and persistence of the price trend, including versus the S&P 500.

  • 12-month return excluding last monthBottom 37%
  • 6-month returnBottom 34%
  • 1-year return vs S&P 500Bottom 45%
  • Distance from 52-week highBottom 27%
  • Trend checklist (0–4)Bottom 38%
Revisions71Positive

Earnings surprises and analyst sentiment (estimate-revision history is being collected).

  • Average EPS surprise, last 4 quartersBottom 48%
  • Consecutive EPS beatsBottom 20%
  • Share of analysts rating BuyTop 10%
  • Upside to consensus price targetTop 28%
Stability57Neutral

Low volatility, shallow drawdowns, low market sensitivity and modest leverage.

  • Volatility, 60 days (lower is better)Bottom 32%
  • Maximum drawdown, 3 yearsTop 30%
  • Beta vs S&P 500 (lower is better)Top 43%

What changed

Latest four quarters versus the same period a year earlier (growth: versus one quarter earlier).

MeasureBeforeNow
Revenue growth (YoY)-88.1%700.0%↑
Gross margin74.0%95.3%↑
Operating margin-5033.2%-728.1%↑
FCF margin-4265.0%-534.2%↑

Fundamental momentum

MeasureNow (TTM)Year / quarter beforeSector rank
Revenue growth (TTM, YoY)700.0%-88.1%↑Top 4%
Gross margin95.3%74.0%↑Top 13%
Operating margin-728.1%-5033.2%↑Bottom 14%
Net margin-668.0%-4831.8%↑—
Free-cash-flow margin-534.2%-4265.0%↑—
Return on invested capital-28.4%—Bottom 43%

Quality of earnings and balance sheet

Accruals (net income − OCF) / assetsLower is better; high accruals can signal weaker earnings quality.
-5.1%
Stock-based compensation / revenueA cost to shareholders through dilution.
131.2%
Net debt / EBITDABelow 1× is conservative; above 3× is high leverage.
Net cash
Interest cover (operating income / interest)How many times operating profit covers interest.
-81.0×

Shareholder returns

Dividend yield (dividends paid, TTM)
0.00%
Net buyback yield (TTM)
-1.87%
Shareholder yield
-1.87%
Share count change, 1 year
+34.5%

Shareholder yield = dividends + net buybacks over the last four quarters, divided by market cap.

Based on the four quarters through Jun 30, 2026 (filed Aug 11, 2026).

Earnings and expectations

Earnings momentum

Consecutive EPS beats
0
Beats in the last 8 reports
3 of 7
Average EPS surprise, last 4
+2.8%
Average 2-day reaction, last 8
-6.5%
Positive 20 days after report
3 of 7

Analysts

Consensus price target
$64.00
Target vs current price
+142.1%
Analysts with a rating
6
Share rating Buy or Strong Buy
100%
Consensus rating
Buy

How the stock reacted to recent reports

Report dateEPS surprise2 days5 days20 days60 days
Aug 12, 2026-6.0%+0.8%+6.7%-10.0%—
May 12, 2026-4.7%+1.0%-4.0%-6.2%+11.8%
Mar 25, 2026+11.0%-35.2%-39.1%-45.9%-47.6%
Nov 6, 2025+10.8%-2.1%+7.6%+40.7%+58.5%
Aug 12, 2025+2.5%+2.0%-0.9%+21.3%+140.7%
May 14, 2025-51.3%-8.1%+2.5%+29.6%+33.3%
Mar 31, 2025-4171.1%-3.6%-20.6%-26.6%-0.1%

Returns from the close before each report. Past reactions do not determine future ones.

Earnings history

Report dateEPSEstimateSurpriseRevenue
Aug 12, 2026-$0.76-$0.72-6.0%—
May 12, 2026-$0.45-$0.43-4.7%$20.0M
Mar 25, 2026-$0.65-$0.73+11.0%—
Nov 6, 2025-$0.66-$0.74+10.8%—
Aug 12, 2025-$0.77-$0.79+2.5%—
May 14, 2025-$1.15-$0.76-51.3%—
Mar 31, 2025-$18.32$0.45-4171.1%—
Dec 6, 2024-$0.06——$2.5M

Valuation in context

MultipleNow5-year median5-year percentileSector rank (cheapness)
EV / Sales66.03×——Bottom 11%
Free-cash-flow yield-7.30%——Bottom 43%
Earnings yield-10.37%——Bottom 45%

Technical state

Trend checklist

  • ✓ Price above 20-day average
  • ✗ Price above 50-day average
  • ✗ Price above 200-day average
  • ✗ 50-day average above 200-day
  • ✓ MACD histogram positive

Trend quality

Days above the 50-day average
0
Days above the 200-day average
0
50-day average slope (20 days)
-5.8%
200-day average slope (20 days)
-3.7%
Distance from 50-day average
-2.1%
Distance from 200-day average
-19.9%
RSI (14)
50.5
Relative volume
0.72×

Risk and drawdowns

Volatility, 60 days (annualized)
66.7%
Volatility vs own 5-year history
39th percentile · Normal for this stock
Beta vs S&P 500 (2 years, weekly)
1.00
Correlation with S&P 500
0.18
Current drawdown from 1-year high
-49.0%
Maximum drawdown, 3 years
-56.8%

Largest declines in the past six years

From peakTo lowDeclineLengthRecovery
Mar 12, 2026Sep 21, 2026-56.8%132 daysNot yet recovered
Jan 31, 2025Apr 8, 2025-52.5%46 days66 days (Jul 15, 2025)
Jul 18, 2025Aug 8, 2025-26.1%15 days23 days (Sep 11, 2025)
Nov 3, 2025Nov 7, 2025-14.0%4 days6 days (Nov 17, 2025)

Declines of 10% or more from a closing high, measured on daily closes.

Financial statements

Market cap
$1.46B
EPS, diluted (TTM)
-$2.74
Revenue (TTM)
$20.0M
52-week range
$21.95 – $53.65
FY 2022FY 2023FY 2024FY 2025
Revenue$0$0$167.5M$0
Gross profit$0$0$167.5M-$2.4M
Operating income-$111.0M-$98.6M$57.6M-$142.9M
Net income-$114.9M-$100.4M$52.2M-$131.1M
EPS (diluted)-$2.63-$2.29$0.08-$3.05
Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
Revenue$2.5M$0$0$0$0$0$20.0M$0
Net income-$24.8M-$29.6M-$32.8M-$33.7M-$30.1M-$34.6M-$24.2M-$44.7M
EPS (diluted)-$0.06-$0.11-$0.75-$0.77-$0.66-$0.87-$0.45-$0.76
FY 2022FY 2023FY 2024FY 2025
Operating cash flow-$99.2M-$86.8M$76.0M-$111.9M
Capital expenditure-$2.0M-$441,000-$1.1M-$794,000
Free cash flow-$101.2M-$87.3M$74.8M-$112.7M
Dividends paid$0$0$0$0
Net share buybacks$1.7M$209,000$68.4M$275.8M

Cash outflows are shown as negative numbers.

Cash and short-term investments
$411.1M
Total assets
$531.6M
Total liabilities
$78.5M
Total debt
$60.4M
Net debt
-$142.2M
Shareholders’ equity
$453.1M

As of Jun 30, 2026 (filed Aug 11, 2026).

Short interest

Shares sold short
5,678,289
Days to cover
10.40
Change vs previous report
-4.1%

FINRA short interest, settlement date Sep 15, 2026.