Stocks · Healthcare · Biotechnology

Nautilus Biotechnolgy, Inc. NAUT

$1.96 +24.84% Close, Oct 2, 2026 · NASDAQ · Market cap $249.4M

Expensive vs sector

Next earnings report: Oct 26, 2026

Scroll or pinch to zoom, drag to move. Daily prices adjusted for splits. Markers: E = earnings (green beat, red miss), S = split, D = dividend.

Three things to know

  1. Over the past year the stock returned +134.7%, ahead of the S&P 500 by 119.6 percentage points.
  2. Earnings beat analyst estimates in each of the last 14 quarters (average surprise over the last four: +21.0%).
  3. The stock is in a downtrend: below its 200-day average, with the 50-day average below the 200-day.

PromtFinance scores

Each score is a percentile within the Healthcare sector (0–100). Under each score: how the stock ranks in its sector on every component. As of Oct 5, 2026.

Growth—Not enough data

How fast revenue, earnings and cash flow are growing.

Quality3Very weak

Returns on capital, margins, earnings quality and balance-sheet strength.

  • Return on invested capitalBottom 34%
  • Gross marginBottom 2%
  • Operating marginBottom 2%
  • Accruals (lower is better)Bottom 33%
Value17Very weak

How cheap the shares are relative to earnings, cash flow and their own history.

  • Earnings yieldBottom 29%
  • Free-cash-flow yieldBottom 24%
  • EBITDA / enterprise valueBottom 28%
  • Sales / enterprise valueBottom 3%
Momentum44Weak

Strength and persistence of the price trend, including versus the S&P 500.

  • 12-month return excluding last monthBottom 46%
  • 6-month returnBottom 8%
  • 1-year return vs S&P 500Top 10%
  • Distance from 52-week highBottom 23%
  • Trend checklist (0–4)Top 39%
Revisions84Strong

Earnings surprises and analyst sentiment (estimate-revision history is being collected).

  • Average EPS surprise, last 4 quartersTop 22%
  • Consecutive EPS beatsTop 2%
  • Share of analysts rating BuyBottom 25%
  • Upside to consensus price targetTop 44%
Stability27Very weak

Low volatility, shallow drawdowns, low market sensitivity and modest leverage.

  • Volatility, 60 days (lower is better)Bottom 4%
  • Maximum drawdown, 3 yearsBottom 31%
  • Beta vs S&P 500 (lower is better)Top 36%

Fundamental momentum

MeasureNow (TTM)Year / quarter beforeSector rank
Gross margin-919.5%—Bottom 2%
Operating margin-33043.7%—Bottom 2%
Net margin-29747.9%——
Free-cash-flow margin-27295.3%——
Return on invested capital-39.5%—Bottom 34%

Quality of earnings and balance sheet

Accruals (net income − OCF) / assetsLower is better; high accruals can signal weaker earnings quality.
-3.8%
Stock-based compensation / revenueA cost to shareholders through dilution.
2887.9%

Shareholder returns

Dividend yield (dividends paid, TTM)
0.00%
Net buyback yield (TTM)
-0.58%
Shareholder yield
-0.58%
Share count change, 1 year
+0.5%
Share count change, 3-year CAGR
+0.6%

Shareholder yield = dividends + net buybacks over the last four quarters, divided by market cap.

Based on the four quarters through Jun 30, 2026 (filed Jul 28, 2026).

Earnings and expectations

Earnings momentum

Consecutive EPS beats
14
Beats in the last 8 reports
8 of 8
Average EPS surprise, last 4
+21.0%
Average 2-day reaction, last 8
-3.6%
Positive 20 days after report
3 of 8

Analysts

Consensus price target
$3.50
Target vs current price
+78.6%
Analysts with a rating
5
Share rating Buy or Strong Buy
60%
Consensus rating
Buy

How the stock reacted to recent reports

Report dateEPS surprise2 days5 days20 days60 days
Jul 28, 2026+18.5%-27.7%-39.2%-47.3%—
Apr 28, 2026+17.2%+0.8%+12.5%-5.4%-31.1%
Feb 26, 2026+21.4%-16.3%-9.3%+35.3%-12.1%
Oct 27, 2025+26.7%+10.7%+9.0%+83.6%+86.1%
Jul 31, 2025+22.6%+0.0%+3.6%-7.6%+90.8%
Apr 29, 2025+7.1%+8.0%+0.8%+13.7%+11.9%
Feb 26, 2025+12.5%-2.7%-17.7%-37.4%-46.6%
Oct 29, 2024+23.5%-1.4%-8.5%-13.2%-34.5%

Returns from the close before each report. Past reactions do not determine future ones.

Earnings history

Report dateEPSEstimateSurpriseRevenue
Jul 28, 2026-$0.11-$0.14+18.5%$190,000
Apr 28, 2026-$0.12-$0.15+17.2%—
Feb 26, 2026-$0.11-$0.14+21.4%—
Oct 27, 2025-$0.11-$0.15+26.7%—
Jul 31, 2025-$0.12-$0.16+22.6%—
Apr 29, 2025-$0.13-$0.14+7.1%—
Feb 26, 2025-$0.14-$0.16+12.5%$9.6M
Oct 29, 2024-$0.13-$0.17+23.5%—

Valuation in context

MultipleNow5-year median5-year percentileSector rank (cheapness)
EV / Sales1389.84×——Bottom 3%
Free-cash-flow yield-20.79%——Bottom 24%
Earnings yield-22.96%——Bottom 29%

Technical state

Trend checklist

  • ✓ Price above 20-day average
  • ✓ Price above 50-day average
  • ✗ Price above 200-day average
  • ✗ 50-day average above 200-day
  • ✓ MACD histogram positive

Trend quality

Days above the 50-day average
5
Days above the 200-day average
0
50-day average slope (20 days)
-21.4%
200-day average slope (20 days)
-4.5%
Distance from 50-day average
+90.4%
Distance from 200-day average
-5.4%
RSI (14)
82.6
Relative volume
4.32×

Risk and drawdowns

Volatility, 60 days (annualized)
130.1%
Volatility vs own 5-year history
97th percentile · High for this stock
Beta vs S&P 500 (2 years, weekly)
0.90
Correlation with S&P 500
0.13
Current drawdown from 1-year high
-50.4%
Maximum drawdown, 3 years
-81.2%

Largest declines in the past six years

From peakTo lowDeclineLengthRecovery
Feb 8, 2021Sep 3, 2025-97.2%1147 daysNot yet recovered

Declines of 10% or more from a closing high, measured on daily closes.

Financial statements

Market cap
$249.4M
EPS, diluted (TTM)
-$0.45
Revenue (TTM)
$190,000
52-week range
$0.82 – $4.31
FY 2021FY 2022FY 2023FY 2024FY 2025
Revenue$0$0$0$0$0
Gross profit-$2.8M$0-$5.7M-$6.4M-$6.5M
Operating income-$50.5M-$63.6M-$76.2M-$81.5M-$66.8M
Net income-$50.3M-$57.9M-$63.7M-$70.8M-$59.0M
EPS (diluted)-$0.60-$0.46-$0.51-$0.56-$0.47
Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
Revenue$0$0$0$0$0$0$0$190,000
Net income-$16.4M-$17.6M-$16.6M-$15.0M-$13.6M-$13.8M-$14.7M-$14.5M
EPS (diluted)-$0.13-$0.14-$0.13-$0.12-$0.11-$0.11-$0.12-$0.11
FY 2021FY 2022FY 2023FY 2024FY 2025
Operating cash flow-$39.2M-$45.8M-$51.7M-$59.1M-$50.7M
Capital expenditure-$2.3M-$2.3M-$2.4M-$2.1M-$1.3M
Free cash flow-$41.5M-$48.1M-$54.2M-$61.3M-$52.0M
Dividends paid$0$0$0$0$0
Net share buybacks-$8.0M$562,000$368,000$1.1M$214,000

Cash outflows are shown as negative numbers.

Cash and short-term investments
$84.0M
Total assets
$163.6M
Total liabilities
$32.5M
Total debt
$27.8M
Net debt
$14.7M
Shareholders’ equity
$131.1M

As of Jun 30, 2026 (filed Jul 28, 2026).

Short interest

Shares sold short
4,082,014
Days to cover
3.24
Change vs previous report
+7.0%

FINRA short interest, settlement date Sep 15, 2026.