Stocks · Healthcare · Biotechnology
Orchestra BioMed Holdings, Inc. OBIO
$5.95 -6.30% Close, Oct 2, 2026 · NASDAQ · Market cap $356.3M
Strong trend
Next earnings report: Nov 9, 2026
Scroll or pinch to zoom, drag to move. Daily prices adjusted for splits. Markers: E = earnings (green beat, red miss), S = split, D = dividend.
Three things to know
- Revenue over the last four quarters was $32.0M, up 986.1% from a year earlier, slowing from 1033.9% a quarter earlier.
- Operating margin widened to -181.4% from -2420.8% a year earlier.
- The diluted share count rose 66.2% in a year.
PromtFinance scores
Each score is a percentile within the Healthcare sector (0–100). Under each score: how the stock ranks in its sector on every component. As of Oct 5, 2026.
How fast revenue, earnings and cash flow are growing.
- Revenue growth (TTM, YoY)Top 4%
- Revenue growth, 3-year CAGRTop 7%
- Revenue growth accelerationBottom 6%
Returns on capital, margins, earnings quality and balance-sheet strength.
- Return on invested capitalBottom 22%
- Gross marginTop 7%
- Operating marginBottom 25%
- Accruals (lower is better)Bottom 19%
- Interest coverBottom 23%
How cheap the shares are relative to earnings, cash flow and their own history.
- Earnings yieldBottom 37%
- Free-cash-flow yieldBottom 28%
- EBITDA / enterprise valueBottom 33%
- Sales / enterprise valueBottom 26%
Strength and persistence of the price trend, including versus the S&P 500.
- 12-month return excluding last monthTop 19%
- 6-month returnTop 25%
- 1-year return vs S&P 500Top 10%
- Distance from 52-week highTop 13%
- Trend checklist (0–4)Top 7%
Earnings surprises and analyst sentiment (estimate-revision history is being collected).
- Average EPS surprise, last 4 quartersTop 16%
- Consecutive EPS beatsTop 25%
- Share of analysts rating BuyTop 10%
- Upside to consensus price targetTop 41%
Low volatility, shallow drawdowns, low market sensitivity and modest leverage.
- Volatility, 60 days (lower is better)Bottom 40%
- Maximum drawdown, 3 yearsBottom 37%
- Beta vs S&P 500 (lower is better)Bottom 24%
What changed
Latest four quarters versus the same period a year earlier (growth: versus one quarter earlier).
| Measure | Before | Now | |
|---|---|---|---|
| Revenue growth (YoY) | 1033.9% | 986.1% | ↓ |
| Gross margin | 92.7% | 99.3% | ↑ |
| Operating margin | -2420.8% | -181.4% | ↑ |
| FCF margin | -2027.9% | -184.8% | ↑ |
Fundamental momentum
| Measure | Now (TTM) | Year / quarter before | Sector rank | |
|---|---|---|---|---|
| Revenue growth (TTM, YoY) | 986.1% | 1033.9% | ↓ | Top 4% |
| Gross margin | 99.3% | 92.7% | ↑ | Top 7% |
| Operating margin | -181.4% | -2420.8% | ↑ | Bottom 25% |
| Net margin | -184.6% | -2367.5% | ↑ | — |
| Free-cash-flow margin | -184.8% | -2027.9% | ↑ | — |
| Return on invested capital | -56.3% | — | Bottom 22% | |
| Revenue growth, 3-year CAGR | 111.6% | — | Top 7% |
Quality of earnings and balance sheet
- Accruals (net income − OCF) / assetsLower is better; high accruals can signal weaker earnings quality.
- -0.6%
- Stock-based compensation / revenueA cost to shareholders through dilution.
- 34.8%
- Receivables growth vs revenue growthReceivables growing much faster than sales can be a warning.
- -1024.7 pp
- Interest cover (operating income / interest)How many times operating profit covers interest.
- -27.6×
Shareholder returns
- Dividend yield (dividends paid, TTM)
- 0.00%
- Net buyback yield (TTM)
- -21.65%
- Shareholder yield
- -21.65%
- Share count change, 1 year
- +66.2%
- Share count change, 3-year CAGR
- +22.6%
Shareholder yield = dividends + net buybacks over the last four quarters, divided by market cap.
Based on the four quarters through Jun 30, 2026 (filed Aug 10, 2026).
Earnings and expectations
Earnings momentum
- Consecutive EPS beats
- 3
- Beats in the last 8 reports
- 6 of 8
- Average EPS surprise, last 4
- +36.7%
- Average 2-day reaction, last 8
- +1.4%
- Positive 20 days after report
- 4 of 8
Analysts
- Consensus price target
- $11.00
- Target vs current price
- +84.9%
- Analysts with a rating
- 6
- Share rating Buy or Strong Buy
- 100%
- Consensus rating
- Buy
How the stock reacted to recent reports
| Report date | EPS surprise | 2 days | 5 days | 20 days | 60 days |
|---|---|---|---|---|---|
| Aug 10, 2026 | +3.1% | +5.2% | +4.0% | +19.8% | — |
| May 12, 2026 | +17.5% | +3.8% | +1.8% | +3.1% | +6.1% |
| Mar 12, 2026 | +131.6% | -4.8% | -2.0% | -8.0% | -15.2% |
| Nov 10, 2025 | -5.3% | -0.8% | +3.4% | +15.2% | -2.6% |
| Aug 12, 2025 | +2.0% | +7.9% | +4.4% | +7.5% | +48.4% |
| Apr 2, 2025 | +0.0% | +8.6% | -13.9% | -8.3% | -14.2% |
| Mar 26, 2025 | +14.0% | -1.4% | -27.0% | -35.8% | -32.2% |
| Nov 12, 2024 | +6.8% | -7.7% | -4.9% | -8.3% | -9.0% |
Returns from the close before each report. Past reactions do not determine future ones.
Earnings history
| Report date | EPS | Estimate | Surprise | Revenue |
|---|---|---|---|---|
| Aug 10, 2026 | -$0.38 | -$0.39 | +3.1% | $88,000 |
| May 12, 2026 | -$0.33 | -$0.40 | +17.5% | $110,000 |
| Mar 12, 2026 | $0.12 | -$0.38 | +131.6% | $30.9M |
| Nov 10, 2025 | -$0.40 | -$0.38 | -5.3% | $861,000 |
| Aug 12, 2025 | -$0.50 | -$0.51 | +2.0% | $836,000 |
| Apr 2, 2025 | -$0.43 | -$0.43 | +0.0% | $253,000 |
| Mar 26, 2025 | -$0.37 | -$0.43 | +14.0% | $253,000 |
| Nov 12, 2024 | -$0.41 | -$0.44 | +6.8% | $987,000 |
Valuation in context
| Multiple | Now | 5-year median | 5-year percentile | Sector rank (cheapness) |
|---|---|---|---|---|
| EV / Sales | 12.72× | — | — | Bottom 26% |
| Free-cash-flow yield | -16.59% | — | — | Bottom 28% |
| Earnings yield | -16.64% | — | — | Bottom 37% |
Technical state
Trend checklist
- ✓ Price above 20-day average
- ✓ Price above 50-day average
- ✓ Price above 200-day average
- ✓ 50-day average above 200-day
- ✗ MACD histogram positive
Trend quality
- Days above the 50-day average
- 46
- Days above the 200-day average
- 40
- 50-day average slope (20 days)
- +18.2%
- 200-day average slope (20 days)
- +3.0%
- Distance from 50-day average
- +15.5%
- Distance from 200-day average
- +35.3%
- RSI (14)
- 55.3
- Relative volume
- 1.10×
Risk and drawdowns
- Volatility, 60 days (annualized)
- 61.0%
- Volatility vs own 5-year history
- 33th percentile · Normal for this stock
- Beta vs S&P 500 (2 years, weekly)
- 1.71
- Correlation with S&P 500
- 0.37
- Current drawdown from 1-year high
- -6.3%
- Maximum drawdown, 3 years
- -78.0%
Largest declines in the past six years
| From peak | To low | Decline | Length | Recovery |
|---|---|---|---|---|
| Apr 12, 2023 | Sep 23, 2025 | -89.4% | 614 days | Not yet recovered |
| Feb 16, 2021 | Feb 14, 2023 | -42.6% | 459 days | 13 days (Mar 6, 2023) |
| Mar 6, 2023 | Mar 17, 2023 | -33.0% | 9 days | 10 days (Mar 31, 2023) |
| Aug 6, 2020 | Nov 4, 2020 | -14.4% | 63 days | 38 days (Dec 30, 2020) |
| Jan 4, 2021 | Jan 27, 2021 | -13.3% | 16 days | 8 days (Feb 8, 2021) |
Declines of 10% or more from a closing high, measured on daily closes.
Financial statements
- Market cap
- $356.3M
- EPS, diluted (TTM)
- -$0.99
- Revenue (TTM)
- $32.0M
- 52-week range
- $2.50 – $6.50
| FY 2021 | FY 2022 | FY 2023 | FY 2024 | FY 2025 | |
|---|---|---|---|---|---|
| Revenue | -$782,000 | $3.5M | $2.8M | $2.6M | $33.5M |
| Gross profit | -$981,000 | $3.2M | $2.6M | $2.4M | $33.3M |
| Operating income | -$21.8M | -$32.7M | -$51.5M | -$64.3M | -$51.8M |
| Net income | -$23.0M | -$33.6M | -$49.1M | -$61.0M | -$52.7M |
| EPS (diluted) | -$0.02 | -$1.32 | -$1.48 | -$1.66 | -$1.11 |
| Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 | Q1 2026 | Q2 2026 | |
|---|---|---|---|---|---|---|---|---|
| Revenue | $987,000 | $253,000 | $868,000 | $836,000 | $861,000 | $30.9M | $110,000 | $88,000 |
| Net income | -$15.4M | -$16.2M | -$18.8M | -$19.4M | -$20.8M | $6.2M | -$20.7M | -$23.8M |
| EPS (diluted) | -$0.41 | -$0.42 | -$0.49 | -$0.50 | -$0.40 | $0.12 | -$0.33 | -$0.38 |
| FY 2021 | FY 2022 | FY 2023 | FY 2024 | FY 2025 | |
|---|---|---|---|---|---|
| Operating cash flow | -$19.4M | -$29.3M | -$46.1M | -$50.6M | -$49.0M |
| Capital expenditure | -$274,000 | -$591,000 | -$78,000 | -$289,000 | -$489,000 |
| Free cash flow | -$19.7M | -$29.9M | -$46.2M | -$50.8M | -$49.5M |
| Dividends paid | $0 | $0 | $0 | $0 | $0 |
| Net share buybacks | $7,000 | $109.8M | $254,000 | $15.0M | $72.0M |
Cash outflows are shown as negative numbers.
- Cash and short-term investments
- $110.0M
- Total assets
- $115.7M
- Total liabilities
- $86.3M
- Total debt
- $70.8M
- Net debt
- $50.3M
- Shareholders’ equity
- $29.4M
As of Jun 30, 2026 (filed Aug 10, 2026).
Short interest
- Shares sold short
- 2,372,557
- Days to cover
- 6.57
- Change vs previous report
- -3.6%
FINRA short interest, settlement date Sep 15, 2026.