Stocks · Healthcare · Biotechnology

Omeros Corporation OMER

$18.61 +0.76% Close, Oct 2, 2026 · NASDAQ · Market cap $1.35B

Strong trend

Next earnings report: Nov 12, 2026

Scroll or pinch to zoom, drag to move. Daily prices adjusted for splits. Markers: E = earnings (green beat, red miss), S = split, D = dividend.

Three things to know

  1. The diluted share count rose 53.0% in a year.
  2. Over the past year the stock returned +349.5%, ahead of the S&P 500 by 334.4 percentage points.
  3. The shares trade at 10.8× trailing earnings, higher than 90% of the company's own readings over the past five years.

PromtFinance scores

Each score is a percentile within the Healthcare sector (0–100). Under each score: how the stock ranks in its sector on every component. As of Oct 5, 2026.

Growth—Not enough data

How fast revenue, earnings and cash flow are growing.

Quality26Very weak

Returns on capital, margins, earnings quality and balance-sheet strength.

  • Return on invested capitalBottom 41%
  • Gross marginTop 12%
  • Operating marginBottom 24%
  • Cash conversion (OCF / net income)Bottom 4%
  • Accruals (lower is better)Bottom 1%
  • Net debt / EBITDA (lower is better)Top 43%
  • Interest coverBottom 45%
Value55Neutral

How cheap the shares are relative to earnings, cash flow and their own history.

  • Earnings yieldTop 4%
  • Free-cash-flow yieldBottom 49%
  • EBITDA / enterprise valueTop 10%
  • Sales / enterprise valueBottom 14%
  • P/E vs own 5-year history (lower is better)Bottom 12%
Momentum96Exceptional

Strength and persistence of the price trend, including versus the S&P 500.

  • 12-month return excluding last monthTop 3%
  • 6-month returnTop 14%
  • 1-year return vs S&P 500Top 3%
  • Distance from 52-week highTop 19%
  • Trend checklist (0–4)Top 20%
Revisions82Strong

Earnings surprises and analyst sentiment (estimate-revision history is being collected).

  • Average EPS surprise, last 4 quartersTop 4%
  • Consecutive EPS beatsTop 15%
  • Share of analysts rating BuyBottom 28%
  • Upside to consensus price targetBottom 43%
Stability35Weak

Low volatility, shallow drawdowns, low market sensitivity and modest leverage.

  • Volatility, 60 days (lower is better)Bottom 18%
  • Maximum drawdown, 3 yearsBottom 41%
  • Beta vs S&P 500 (lower is better)Bottom 39%
  • Net debt / EBITDA (lower is better)Top 43%

Fundamental momentum

MeasureNow (TTM)Year / quarter beforeSector rank
Gross margin95.8%—Top 12%
Operating margin-189.5%—Bottom 24%
Net margin324.9%——
Free-cash-flow margin-178.9%——
Return on invested capital-31.1%—Bottom 41%

Quality of earnings and balance sheet

Cash conversion (OCF / net income)Above 1× means profits are backed by cash.
-0.55×
Accruals (net income − OCF) / assetsLower is better; high accruals can signal weaker earnings quality.
67.5%
Stock-based compensation / revenueA cost to shareholders through dilution.
13.8%
Net debt / EBITDABelow 1× is conservative; above 3× is high leverage.
0.60×
Interest cover (operating income / interest)How many times operating profit covers interest.
-3.3×

Shareholder returns

Dividend yield (dividends paid, TTM)
0.00%
Net buyback yield (TTM)
-3.39%
Shareholder yield
-3.39%
Share count change, 1 year
+53.0%
Share count change, 3-year CAGR
+12.6%

Shareholder yield = dividends + net buybacks over the last four quarters, divided by market cap.

Based on the four quarters through Jun 30, 2026 (filed Aug 12, 2026).

Earnings and expectations

Earnings momentum

Consecutive EPS beats
5
Beats in the last 8 reports
7 of 8
Average EPS surprise, last 4
+100.0%
Average 2-day reaction, last 8
+1.9%
Positive 20 days after report
4 of 8

Analysts

Consensus price target
$27.50
Target vs current price
+47.8%
Analysts with a rating
19
Share rating Buy or Strong Buy
63%
Consensus rating
Buy

How the stock reacted to recent reports

Report dateEPS surprise2 days5 days20 days60 days
Aug 13, 2026+155.9%+26.5%+34.1%+35.6%—
May 13, 2026+40.0%-2.6%-18.9%-30.9%-10.2%
Mar 31, 2026+670.9%+7.6%+11.9%+49.5%+9.3%
Nov 13, 2025+19.0%-8.9%+19.3%+53.7%+62.1%
Aug 14, 2025+21.8%-3.5%-1.9%-1.6%+54.1%
May 15, 2025-2.5%+0.5%-20.9%-9.7%+5.3%
Mar 31, 2025+30.4%-3.0%-16.6%-14.2%-58.7%
Nov 13, 2024+20.0%-1.6%+41.5%+111.5%+104.7%

Returns from the close before each report. Past reactions do not determine future ones.

Earnings history

Report dateEPSEstimateSurpriseRevenue
Aug 13, 2026$0.15-$0.27+155.9%$28.5M
May 13, 2026-$0.24-$0.40+40.0%$9.9M
Mar 31, 2026$3.14-$0.55+670.9%—
Nov 13, 2025-$0.47-$0.58+19.0%—
Aug 14, 2025-$0.43-$0.55+21.8%—
May 15, 2025-$0.58-$0.57-2.5%—
Mar 31, 2025-$0.54-$0.78+30.4%—
Nov 13, 2024-$0.56-$0.70+20.0%—

Valuation in context

MultipleNow5-year median5-year percentileSector rank (cheapness)
P/E (trailing)10.8×4.5×90thTop 4%
P/E (forward)20.5×———
EV / EBITDA10.5×——Top 10%
EV / Sales37.18×——Bottom 14%
Free-cash-flow yield-5.10%——Bottom 49%
Earnings yield9.24%——Top 4%

P/E over the past five years

Range 0.9× – 12.6× since Dec 31, 2021. Each point: price on the filing date divided by trailing-twelve-month EPS known then.

Technical state

Trend checklist

  • ✗ Price above 20-day average
  • ✓ Price above 50-day average
  • ✓ Price above 200-day average
  • ✓ 50-day average above 200-day
  • ✗ MACD histogram positive

Trend quality

Days above the 50-day average
49
Days above the 200-day average
49
50-day average slope (20 days)
+27.0%
200-day average slope (20 days)
+7.5%
Distance from 50-day average
+9.9%
Distance from 200-day average
+43.2%
RSI (14)
51.2
Relative volume
0.64×

Risk and drawdowns

Volatility, 60 days (annualized)
80.0%
Volatility vs own 5-year history
22th percentile · Normal for this stock
Beta vs S&P 500 (2 years, weekly)
1.31
Correlation with S&P 500
0.15
Current drawdown from 1-year high
-11.6%
Maximum drawdown, 3 years
-75.6%

Largest declines in the past six years

From peakTo lowDeclineLengthRecovery
Feb 19, 2021Oct 27, 2023-95.4%677 daysNot yet recovered
Oct 16, 2020Oct 30, 2020-12.0%10 days10 days (Nov 13, 2020)

Declines of 10% or more from a closing high, measured on daily closes.

Financial statements

Market cap
$1.35B
P/E (TTM)
10.8
EPS, diluted (TTM)
$1.72
Revenue (TTM)
$38.4M
52-week range
$4.06 – $21.24
FY 2021FY 2022FY 2023FY 2024FY 2025
Revenue$0$0$0$0$0
Gross profit-$1.4M$0$0$0$0
Operating income-$173.6M-$163.4M-$164.5M-$169.3M-$122.8M
Net income-$111.4M$47.4M-$117.8M-$156.8M-$3.4M
EPS (diluted)-$1.79$0.46-$1.88-$2.70-$0.05
Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
Revenue$0$0$0$0$0$0$9.9M$28.5M
Net income-$32.2M-$31.4M-$33.5M-$25.4M-$30.9M$86.5M$56.1M$13.2M
EPS (diluted)-$0.56-$0.54-$0.58-$0.43-$0.47$1.42$0.62$0.15
FY 2021FY 2022FY 2023FY 2024FY 2025
Operating cash flow-$109.7M-$86.5M$74.7M-$148.8M-$116.1M
Capital expenditure-$277,000-$113,000-$426,000-$165,000-$65,000
Free cash flow-$110.0M-$86.6M$74.3M-$149.0M-$116.2M
Dividends paid$0$0$0$0$0
Net share buybacks$8.4M$415,000-$4.7M-$11.9M$47.0M

Cash outflows are shown as negative numbers.

Cash and short-term investments
$132.0M
Total assets
$286.8M
Total liabilities
$338.2M
Total debt
$83.8M
Net debt
$81.8M
Shareholders’ equity
-$51.3M

As of Jun 30, 2026 (filed Aug 12, 2026).

Short interest

Shares sold short
12,491,576
Days to cover
9.31
Change vs previous report
-2.1%

FINRA short interest, settlement date Sep 15, 2026.