Stocks · Healthcare · Biotechnology

PTC Therapeutics, Inc. PTCT

$63.46 -1.04% Close, Oct 2, 2026 · NASDAQ · Market cap $5.30B

High qualityLow risk

Next earnings report: Nov 3, 2026

Scroll or pinch to zoom, drag to move. Daily prices adjusted for splits. Markers: E = earnings (green beat, red miss), S = split, D = dividend.

Three things to know

  1. Diluted EPS over the last four quarters was $-0.58, down 108.3% year over year.
  2. Operating margin narrowed to 11.5% from 40.7% a year earlier.
  3. The diluted share count rose 17.7% in a year.

PromtFinance scores

Each score is a percentile within the Healthcare sector (0–100). Under each score: how the stock ranks in its sector on every component. As of Oct 5, 2026.

Growth33Weak

How fast revenue, earnings and cash flow are growing.

  • Revenue growth (TTM, YoY)Bottom 12%
  • EPS growth (TTM, YoY)Bottom 17%
  • FCF growth (TTM, YoY)Bottom 11%
  • Revenue growth, 3-year CAGRTop 18%
  • Revenue growth accelerationTop 13%
Quality86Strong

Returns on capital, margins, earnings quality and balance-sheet strength.

  • Return on invested capitalTop 28%
  • Gross marginTop 29%
  • Operating marginTop 23%
  • Accruals (lower is better)Bottom 18%
  • Net debt / EBITDA (lower is better)Top 12%
  • Interest coverTop 42%
Value63Neutral

How cheap the shares are relative to earnings, cash flow and their own history.

  • Earnings yieldTop 32%
  • Free-cash-flow yieldBottom 46%
  • EBITDA / enterprise valueTop 29%
  • Sales / enterprise valueBottom 48%
Momentum35Weak

Strength and persistence of the price trend, including versus the S&P 500.

  • 12-month return excluding last monthBottom 46%
  • 6-month returnBottom 36%
  • 1-year return vs S&P 500Bottom 44%
  • Distance from 52-week highTop 47%
  • Trend checklist (0–4)Bottom 14%
Revisions26Very weak

Earnings surprises and analyst sentiment (estimate-revision history is being collected).

  • Average EPS surprise, last 4 quartersBottom 14%
  • Consecutive EPS beatsTop 35%
  • Share of analysts rating BuyBottom 32%
  • Upside to consensus price targetTop 48%
Stability91Exceptional

Low volatility, shallow drawdowns, low market sensitivity and modest leverage.

  • Volatility, 60 days (lower is better)Top 20%
  • Maximum drawdown, 3 yearsTop 10%
  • Beta vs S&P 500 (lower is better)Top 45%
  • Net debt / EBITDA (lower is better)Top 12%

What changed

Latest four quarters versus the same period a year earlier (growth: versus one quarter earlier).

MeasureBeforeNow
Revenue growth (YoY)-53.3%-42.8%↑
EPS growth (YoY)-135.8%-108.3%↑
Gross margin97.1%82.1%↓
Operating margin40.7%11.5%↓
FCF margin38.6%-33.0%↓

Fundamental momentum

MeasureNow (TTM)Year / quarter beforeSector rank
Revenue growth (TTM, YoY)-42.8%-53.3%↑Bottom 12%
EPS growth (TTM, YoY)-108.3%-135.8%↑Bottom 17%
Gross margin82.1%97.1%↓Top 29%
Operating margin11.5%40.7%↓Top 23%
Net margin-3.8%35.6%↓—
Free-cash-flow margin-33.0%38.6%↓—
Return on invested capital2.6%—Top 28%
Revenue growth, 3-year CAGR35.3%—Top 18%

Quality of earnings and balance sheet

Accruals (net income − OCF) / assetsLower is better; high accruals can signal weaker earnings quality.
-0.2%
Stock-based compensation / revenueA cost to shareholders through dilution.
8.4%
Receivables growth vs revenue growthReceivables growing much faster than sales can be a warning.
+64.7 pp
Net debt / EBITDABelow 1× is conservative; above 3× is high leverage.
-2.04×
Interest cover (operating income / interest)How many times operating profit covers interest.
0.6×

Shareholder returns

Dividend yield (dividends paid, TTM)
0.00%
Net buyback yield (TTM)
-1.93%
Shareholder yield
-1.93%
Share count change, 1 year
+17.7%
Share count change, 3-year CAGR
+7.2%

Shareholder yield = dividends + net buybacks over the last four quarters, divided by market cap.

Based on the four quarters through Jun 30, 2026 (filed Jul 30, 2026).

Earnings and expectations

Earnings momentum

Consecutive EPS beats
2
Beats in the last 8 reports
7 of 8
Average EPS surprise, last 4
-48.9%
Average 2-day reaction, last 8
-1.9%
Positive 20 days after report
6 of 8

Analysts

Consensus price target
$106.00
Target vs current price
+67.0%
Analysts with a rating
26
Share rating Buy or Strong Buy
65%
Consensus rating
Buy

How the stock reacted to recent reports

Report dateEPS surprise2 days5 days20 days60 days
Jul 30, 2026+289.3%+1.4%-7.1%-2.4%—
May 7, 2026+93.3%-3.1%+10.4%+6.1%+2.3%
Feb 19, 2026-695.2%+1.4%-1.7%-2.8%+5.5%
Nov 4, 2025+116.8%-0.3%+6.7%+15.6%+11.2%
Aug 7, 2025+22.4%-1.9%-6.2%+12.9%+32.6%
May 6, 2025+1029.6%-11.0%+13.2%+24.7%+28.2%
Feb 27, 2025+24.1%-0.8%+1.9%+8.5%-10.7%
Nov 7, 2024+9.7%-0.5%+2.0%+12.1%+15.8%

Returns from the close before each report. Past reactions do not determine future ones.

Earnings history

Report dateEPSEstimateSurpriseRevenue
Jul 30, 2026$0.92$0.24+289.3%$360.5M
May 7, 2026-$0.03-$0.45+93.3%$272.6M
Feb 19, 2026-$1.67-$0.21-695.2%$164.7M
Nov 4, 2025$0.20-$1.19+116.8%$211.0M
Aug 7, 2025-$0.83-$1.07+22.4%$178.9M
May 6, 2025$10.04-$1.08+1029.6%$1.18B
Feb 27, 2025-$0.85-$1.12+24.1%$213.2M
Nov 7, 2024-$1.39-$1.54+9.7%$196.8M

Valuation in context

MultipleNow5-year median5-year percentileSector rank (cheapness)
P/E (forward)49.9×———
EV / EBITDA28.5×——Top 29%
EV / Sales4.90×——Bottom 48%
Free-cash-flow yield-6.28%——Bottom 46%
Earnings yield-0.91%——Top 32%

P/E over the past five years

Range 5.6× – 9.0× since Mar 31, 2025. Each point: price on the filing date divided by trailing-twelve-month EPS known then.

Technical state

Trend checklist

  • ✗ Price above 20-day average
  • ✗ Price above 50-day average
  • ✗ Price above 200-day average
  • ✗ 50-day average above 200-day
  • ✓ MACD histogram positive

Trend quality

Days above the 50-day average
0
Days above the 200-day average
0
50-day average slope (20 days)
-8.6%
200-day average slope (20 days)
-1.7%
Distance from 50-day average
-8.7%
Distance from 200-day average
-12.1%
RSI (14)
38.5
Relative volume
0.71×

Risk and drawdowns

Volatility, 60 days (annualized)
38.9%
Volatility vs own 5-year history
18th percentile · Low for this stock
Beta vs S&P 500 (2 years, weekly)
1.03
Correlation with S&P 500
0.35
Current drawdown from 1-year high
-29.1%
Maximum drawdown, 3 years
-36.7%

Largest declines in the past six years

From peakTo lowDeclineLengthRecovery
Jan 7, 2021Nov 2, 2023-73.8%710 days503 days (Nov 5, 2025)
Jul 9, 2026Sep 24, 2026-30.4%54 daysNot yet recovered
Nov 26, 2025Mar 6, 2026-27.2%67 days83 days (Jul 7, 2026)
Dec 18, 2020Jan 4, 2021-10.6%9 days3 days (Jan 7, 2021)
Dec 4, 2020Dec 7, 2020-10.0%1 days5 days (Dec 14, 2020)

Declines of 10% or more from a closing high, measured on daily closes.

Financial statements

Market cap
$5.30B
EPS, diluted (TTM)
-$0.58
Revenue (TTM)
$1.01B
52-week range
$61.16 – $90.87
FY 2021FY 2022FY 2023FY 2024FY 2025
Revenue$538.6M$698.8M$937.8M$806.8M$1.73B
Gross profit$506.3M$654.1M$872.3M$749.4M$1.66B
Operating income-$374.4M-$447.4M-$439.5M-$302.6M$856.5M
Net income-$523.9M-$559.0M-$626.6M-$363.3M$682.6M
EPS (diluted)-$7.43-$7.79-$8.37-$4.73$7.78
Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
Revenue$196.8M$213.2M$1.18B$178.9M$211.0M$164.7M$272.6M$360.5M
Net income-$106.7M-$65.9M$866.6M-$64.8M$15.9M-$135.0M-$2.8M$83.5M
EPS (diluted)-$1.39-$0.85$10.04-$0.83$0.20-$1.67-$0.03$0.92
FY 2021FY 2022FY 2023FY 2024FY 2025
Operating cash flow-$251.3M-$356.7M-$158.4M-$107.7M$711.2M
Capital expenditure-$85.3M-$152.5M-$120.6M-$74.2M-$300.0M
Free cash flow-$336.7M-$509.1M-$279.0M-$181.9M$411.2M
Dividends paid$0$0$0$0$0
Net share buybacks$23.1M$50.0M$0$0$99.0M

Cash outflows are shown as negative numbers.

Cash and short-term investments
$2.23B
Total assets
$3.25B
Total liabilities
$3.42B
Total debt
$696.5M
Net debt
-$353.4M
Shareholders’ equity
-$165.4M

As of Jun 30, 2026 (filed Jul 30, 2026).

Short interest

Shares sold short
9,738,919
Days to cover
11.03
Change vs previous report
-0.9%

FINRA short interest, settlement date Sep 15, 2026.