Stocks · Healthcare · Drug Manufacturers - Specialty & Generic
Talphera, Inc. TLPH
$1.13 +0.89% Close, Oct 2, 2026 · NASDAQ · Market cap $58.6M
Expensive vs sector
Next earnings report: Nov 11, 2026
Scroll or pinch to zoom, drag to move. Daily prices adjusted for splits. Markers: E = earnings (green beat, red miss), S = split, D = dividend.
Three things to know
- Revenue over the last four quarters was $1,000, down 96.3% from a year earlier.
- Operating margin narrowed to -1474700.0% from -49459.3% a year earlier.
- The diluted share count rose 118.7% in a year.
PromtFinance scores
Each score is a percentile within the Healthcare sector (0–100). Under each score: how the stock ranks in its sector on every component. As of Oct 5, 2026.
How fast revenue, earnings and cash flow are growing.
- Revenue growth (TTM, YoY)Bottom 5%
- Revenue growth accelerationTop 46%
Returns on capital, margins, earnings quality and balance-sheet strength.
- Return on invested capitalBottom 18%
- Gross marginTop 2%
- Operating marginBottom 1%
- Accruals (lower is better)Top 33%
How cheap the shares are relative to earnings, cash flow and their own history.
- Earnings yieldBottom 26%
- Free-cash-flow yieldBottom 24%
- EBITDA / enterprise valueBottom 25%
- Sales / enterprise valueBottom 1%
Strength and persistence of the price trend, including versus the S&P 500.
- 12-month return excluding last monthTop 45%
- 6-month returnTop 17%
- 1-year return vs S&P 500Top 43%
- Distance from 52-week highTop 43%
- Trend checklist (0–4)Top 39%
Earnings surprises and analyst sentiment (estimate-revision history is being collected).
- Average EPS surprise, last 4 quartersTop 47%
- Consecutive EPS beatsTop 25%
- Upside to consensus price targetTop 24%
Low volatility, shallow drawdowns, low market sensitivity and modest leverage.
- Volatility, 60 days (lower is better)Top 45%
- Maximum drawdown, 3 yearsBottom 45%
- Beta vs S&P 500 (lower is better)Bottom 46%
What changed
Latest four quarters versus the same period a year earlier (growth: versus one quarter earlier).
| Measure | Before | Now | |
|---|---|---|---|
| Revenue growth (YoY) | -96.3% | -96.3% | → |
| Gross margin | -16733.3% | 100.0% | ↑ |
| Operating margin | -49459.3% | -1474700.0% | ↓ |
| FCF margin | -42992.6% | -1227000.0% | ↓ |
Fundamental momentum
| Measure | Now (TTM) | Year / quarter before | Sector rank | |
|---|---|---|---|---|
| Revenue growth (TTM, YoY) | -96.3% | -96.3% | → | Bottom 5% |
| Gross margin | 100.0% | -16733.3% | ↑ | Top 2% |
| Operating margin | -1474700.0% | -49459.3% | ↓ | Bottom 1% |
| Net margin | -1507600.0% | -41870.4% | ↓ | — |
| Free-cash-flow margin | -1227000.0% | -42992.6% | ↓ | — |
| Return on invested capital | -65.2% | — | Bottom 18% |
Quality of earnings and balance sheet
- Accruals (net income − OCF) / assetsLower is better; high accruals can signal weaker earnings quality.
- -10.5%
- Stock-based compensation / revenueA cost to shareholders through dilution.
- 79400.0%
- Net debt / EBITDABelow 1× is conservative; above 3× is high leverage.
- Net cash
Shareholder returns
- Dividend yield (dividends paid, TTM)
- 0.00%
- Net buyback yield (TTM)
- -37.83%
- Shareholder yield
- -37.83%
- Share count change, 1 year
- +118.7%
- Share count change, 3-year CAGR
- +90.5%
Shareholder yield = dividends + net buybacks over the last four quarters, divided by market cap.
Based on the four quarters through Jun 30, 2026 (filed Aug 12, 2026).
Earnings and expectations
Earnings momentum
- Consecutive EPS beats
- 3
- Beats in the last 8 reports
- 7 of 8
- Average EPS surprise, last 4
- +5.0%
- Average 2-day reaction, last 8
- -4.1%
- Positive 20 days after report
- 1 of 8
Analysts
- Consensus price target
- $3.00
- Target vs current price
- +165.5%
How the stock reacted to recent reports
| Report date | EPS surprise | 2 days | 5 days | 20 days | 60 days |
|---|---|---|---|---|---|
| Aug 13, 2026 | +4.0% | -13.6% | -15.0% | -11.4% | — |
| May 13, 2026 | +42.9% | +5.1% | -3.0% | -5.7% | +66.8% |
| Mar 23, 2026 | +20.0% | -3.8% | -11.0% | -6.1% | +10.6% |
| Nov 12, 2025 | -46.7% | +0.0% | +3.9% | -3.1% | -35.5% |
| Aug 14, 2025 | +16.7% | -0.7% | +12.6% | +130.3% | +168.2% |
| May 14, 2025 | +41.2% | -1.9% | -0.8% | -1.3% | -21.2% |
| Mar 31, 2025 | +66.7% | -15.5% | -12.8% | -18.2% | -23.7% |
| Nov 13, 2024 | +35.0% | -2.2% | -26.4% | -23.1% | -31.9% |
Returns from the close before each report. Past reactions do not determine future ones.
Earnings history
| Report date | EPS | Estimate | Surprise | Revenue |
|---|---|---|---|---|
| Aug 13, 2026 | -$0.06 | -$0.06 | +4.0% | — |
| May 13, 2026 | -$0.04 | -$0.07 | +42.9% | — |
| Mar 23, 2026 | -$0.06 | -$0.08 | +20.0% | — |
| Nov 12, 2025 | -$0.11 | -$0.08 | -46.7% | $1,000 |
| Aug 14, 2025 | -$0.10 | -$0.12 | +16.7% | — |
| May 14, 2025 | -$0.10 | -$0.17 | +41.2% | $27,000 |
| Mar 31, 2025 | -$0.07 | -$0.21 | +66.7% | — |
| Nov 13, 2024 | -$0.13 | -$0.20 | +35.0% | — |
Valuation in context
| Multiple | Now | 5-year median | 5-year percentile | Sector rank (cheapness) |
|---|---|---|---|---|
| EV / Sales | 57904.55× | — | — | Bottom 1% |
| Free-cash-flow yield | -20.92% | — | — | Bottom 24% |
| Earnings yield | -28.25% | — | — | Bottom 26% |
P/E over the past five years
Range 0.1× – 0.8× since Jun 30, 2022. Each point: price on the filing date divided by trailing-twelve-month EPS known then.
Technical state
Trend checklist
- ✗ Price above 20-day average
- ✗ Price above 50-day average
- ✓ Price above 200-day average
- ✓ 50-day average above 200-day
- ✗ MACD histogram positive
Trend quality
- Days above the 50-day average
- 0
- Days above the 200-day average
- 74
- 50-day average slope (20 days)
- -2.0%
- 200-day average slope (20 days)
- -1.0%
- Distance from 50-day average
- -8.9%
- Distance from 200-day average
- +11.3%
- RSI (14)
- 37.4
- Relative volume
- 3.04×
Risk and drawdowns
- Volatility, 60 days (annualized)
- 53.4%
- Volatility vs own 5-year history
- 4th percentile · Low for this stock
- Beta vs S&P 500 (2 years, weekly)
- 1.18
- Correlation with S&P 500
- 0.20
- Current drawdown from 1-year high
- -23.1%
- Maximum drawdown, 3 years
- -73.4%
Largest declines in the past six years
| From peak | To low | Decline | Length | Recovery |
|---|---|---|---|---|
| Feb 9, 2021 | Aug 7, 2025 | -99.3% | 1128 days | Not yet recovered |
| Oct 12, 2020 | Dec 29, 2020 | -40.4% | 54 days | 9 days (Jan 12, 2021) |
| Jan 19, 2021 | Jan 21, 2021 | -18.7% | 2 days | 2 days (Jan 25, 2021) |
| Jan 12, 2021 | Jan 14, 2021 | -14.7% | 2 days | 2 days (Jan 19, 2021) |
| Sep 28, 2020 | Oct 6, 2020 | -13.1% | 6 days | 2 days (Oct 8, 2020) |
Declines of 10% or more from a closing high, measured on daily closes.
Financial statements
- Market cap
- $58.6M
- EPS, diluted (TTM)
- -$0.32
- Revenue (TTM)
- $1,000
- 52-week range
- $0.69 – $1.57
| FY 2021 | FY 2022 | FY 2023 | FY 2024 | FY 2025 | |
|---|---|---|---|---|---|
| Revenue | $378,000 | $0 | $651,000 | $0 | $28,000 |
| Gross profit | -$2.6M | -$1.6M | -$4.9M | -$6.7M | $28,000 |
| Operating income | -$18.1M | -$20.4M | -$16.9M | -$15.3M | -$13.5M |
| Net income | -$35.1M | $42.5M | -$18.4M | -$13.0M | -$14.3M |
| EPS (diluted) | -$5.86 | $5.72 | -$1.29 | -$0.50 | -$0.34 |
| Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | Q4 2025 | Q1 2026 | Q2 2026 | |
|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $27,000 | $0 | $1,000 | $0 | $0 | $0 |
| Net income | -$3.4M | -$1.9M | -$2.6M | -$3.5M | -$4.4M | -$3.8M | -$2.6M | -$4.3M |
| EPS (diluted) | -$0.13 | -$0.07 | -$0.10 | -$0.10 | -$0.11 | -$0.09 | -$0.06 | -$0.06 |
| FY 2021 | FY 2022 | FY 2023 | FY 2024 | FY 2025 | |
|---|---|---|---|---|---|
| Operating cash flow | -$30.0M | -$28.3M | -$17.5M | -$12.7M | -$11.4M |
| Capital expenditure | -$1.8M | -$364,000 | -$100,000 | $0 | $0 |
| Free cash flow | -$31.8M | -$28.7M | -$17.6M | -$12.7M | -$11.4M |
| Dividends paid | $0 | $0 | $0 | $0 | $0 |
| Net share buybacks | $50.3M | $8.0M | $8.9M | $5.9M | $22.7M |
Cash outflows are shown as negative numbers.
- Cash and short-term investments
- $17.1M
- Total assets
- $26.8M
- Total liabilities
- $12.4M
- Total debt
- $0
- Net debt
- -$742,000
- Shareholders’ equity
- $14.4M
As of Jun 30, 2026 (filed Aug 12, 2026).
Short interest
- Shares sold short
- 700,723
- Days to cover
- 6.41
- Change vs previous report
- +37.8%
FINRA short interest, settlement date Sep 15, 2026.
Stock splits
- Oct 26, 2022
- 1-for-20