Stocks · Healthcare · Biotechnology

Ligand Pharmaceuticals Incorporated LGND

$306.77 +1.26% Close, Oct 5, 2026 · NASDAQ · Market cap $6.07B

Strong growthHigh qualityStrong trendLow risk

Next earnings report: Nov 5, 2026

Scroll or pinch to zoom, drag to move. Daily prices adjusted for splits. Markers: E = earnings (green beat, red miss), S = split, D = dividend.

Three things to know

  1. Operating margin widened to 34.7% from -18.3% a year earlier.
  2. Revenue over the last four quarters was $290.5M, up 54.9% from a year earlier, accelerating from 51.2% a quarter earlier.
  3. The diluted share count rose 9.6% in a year.

PromtFinance scores

Each score is a percentile within the Healthcare sector (0–100). Under each score: how the stock ranks in its sector on every component. As of Oct 6, 2026.

Growth91Exceptional

How fast revenue, earnings and cash flow are growing.

  • Revenue growth (TTM, YoY)Top 15%
  • FCF growth (TTM, YoY)Top 7%
  • Revenue growth, 3-year CAGRTop 47%
  • Revenue growth accelerationTop 21%
Quality84Strong

Returns on capital, margins, earnings quality and balance-sheet strength.

  • Return on invested capitalTop 26%
  • Gross marginTop 8%
  • Operating marginTop 5%
  • Cash conversion (OCF / net income)Bottom 17%
  • Accruals (lower is better)Bottom 12%
  • Net debt / EBITDA (lower is better)Top 41%
  • Interest coverTop 10%
Value66Positive

How cheap the shares are relative to earnings, cash flow and their own history.

  • Earnings yieldTop 17%
  • Free-cash-flow yieldTop 29%
  • EBITDA / enterprise valueTop 25%
  • Sales / enterprise valueBottom 19%
  • P/E vs own 5-year history (lower is better)Top 50%
Momentum90Exceptional

Strength and persistence of the price trend, including versus the S&P 500.

  • 12-month return excluding last monthTop 28%
  • 6-month returnTop 21%
  • 1-year return vs S&P 500Top 22%
  • Distance from 52-week highTop 11%
  • Trend checklist (0–4)Top 10%
Revisions45Neutral

Earnings surprises and analyst sentiment (estimate-revision history is being collected).

  • Average EPS surprise, last 4 quartersTop 20%
  • Consecutive EPS beatsBottom 49%
  • Share of analysts rating BuyBottom 42%
  • Upside to consensus price targetBottom 21%
Stability91Exceptional

Low volatility, shallow drawdowns, low market sensitivity and modest leverage.

  • Volatility, 60 days (lower is better)Top 7%
  • Maximum drawdown, 3 yearsTop 3%
  • Beta vs S&P 500 (lower is better)Top 38%
  • Net debt / EBITDA (lower is better)Top 41%

What changed

Latest four quarters versus the same period a year earlier (growth: versus one quarter earlier).

MeasureBeforeNow
Revenue growth (YoY)51.2%54.9%↑
Gross margin87.7%98.6%↑
Operating margin-18.3%34.7%↑
FCF margin21.3%45.2%↑

Fundamental momentum

MeasureNow (TTM)Year / quarter beforeSector rank
Revenue growth (TTM, YoY)54.9%51.2%↑Top 15%
Gross margin98.6%87.7%↑Top 8%
Operating margin34.7%-18.3%↑Top 5%
Net margin67.9%-40.4%↑—
Free-cash-flow margin45.2%21.3%↑—
Return on invested capital3.9%—Top 26%
Revenue growth, 3-year CAGR11.0%—Top 47%

Quality of earnings and balance sheet

Cash conversion (OCF / net income)Above 1× means profits are backed by cash.
0.67×
Accruals (net income − OCF) / assetsLower is better; high accruals can signal weaker earnings quality.
3.0%
Stock-based compensation / revenueA cost to shareholders through dilution.
18.3%
Receivables growth vs revenue growthReceivables growing much faster than sales can be a warning.
+11.1 pp
Net debt / EBITDABelow 1× is conservative; above 3× is high leverage.
0.46×
Interest cover (operating income / interest)How many times operating profit covers interest.
16.3×

Shareholder returns

Dividend yield (dividends paid, TTM)
0.00%
Net buyback yield (TTM)
-2.60%
Shareholder yield
-2.60%
Share count change, 1 year
+9.6%
Share count change, 3-year CAGR
+7.2%

Shareholder yield = dividends + net buybacks over the last four quarters, divided by market cap.

Based on the four quarters through Jun 30, 2026 (filed Aug 7, 2026).

Earnings and expectations

Earnings momentum

Consecutive EPS beats
1
Beats in the last 8 reports
5 of 8
Average EPS surprise, last 4
+25.4%
Average 2-day reaction, last 8
+2.7%
Positive 20 days after report
4 of 8

Analysts

Consensus price target
$339.43
Target vs current price
+10.6%
Analysts with a rating
18
Share rating Buy or Strong Buy
72%
Consensus rating
Buy

How the stock reacted to recent reports

Report dateEPS surprise2 days5 days20 days60 days
Aug 6, 2026+17.9%-0.8%-3.1%-5.2%—
May 14, 2026-11.4%-1.0%-1.6%+15.1%+33.7%
Feb 26, 2026+38.4%+2.5%+9.2%+6.9%+16.1%
Nov 6, 2025+56.9%+9.4%+8.0%-1.0%+4.4%
Aug 7, 2025+12.7%+2.8%+9.6%+17.8%+31.4%
May 8, 2025+9.9%-2.9%-0.5%-1.4%+28.2%
Feb 27, 2025-219.7%+0.6%+0.3%-6.0%-11.9%
Nov 7, 2024-128.9%+11.1%+4.4%+5.7%+0.4%

Returns from the close before each report. Past reactions do not determine future ones.

Earnings history

Report dateEPSEstimateSurpriseRevenue
Aug 6, 2026$2.37$2.01+17.9%$63.7M
May 14, 2026$1.63$1.84-11.4%$51.7M
Feb 26, 2026$2.02$1.46+38.4%$59.7M
Nov 6, 2025$3.09$1.97+56.9%$115.5M
Aug 7, 2025$1.60$1.42+12.7%$47.6M
May 8, 2025$1.33$1.21+9.9%$45.3M
Feb 27, 2025-$1.64$1.37-219.7%$42.8M
Nov 7, 2024-$0.39$1.35-128.9%$51.8M

Valuation in context

MultipleNow5-year median5-year percentileSector rank (cheapness)
P/E (trailing)32.8×34.0×47thTop 17%
P/E (forward)33.0×———
EV / EBITDA22.6×——Top 25%
EV / Sales21.33×——Bottom 19%
Free-cash-flow yield2.16%——Top 29%
Earnings yield3.05%——Top 17%

P/E over the past five years

Range 15.5× – 97.8× since Jun 30, 2021. Each point: price on the filing date divided by trailing-twelve-month EPS known then.

Technical state

Trend checklist

  • ✓ Price above 20-day average
  • ✓ Price above 50-day average
  • ✓ Price above 200-day average
  • ✓ 50-day average above 200-day
  • ✓ MACD histogram positive

Trend quality

Days above the 50-day average
10
Days above the 200-day average
332
50-day average slope (20 days)
-1.9%
200-day average slope (20 days)
+4.3%
Distance from 50-day average
+5.1%
Distance from 200-day average
+26.6%
RSI (14)
60.0
Relative volume
0.61×

Risk and drawdowns

Volatility, 60 days (annualized)
28.7%
Volatility vs own 5-year history
6th percentile · Low for this stock
Beta vs S&P 500 (2 years, weekly)
0.93
Correlation with S&P 500
0.42
Current drawdown from 1-year high
-4.9%
Maximum drawdown, 3 years
-25.6%

Largest declines in the past six years

From peakTo lowDeclineLengthRecovery
Feb 9, 2021Jun 13, 2022-65.5%338 days775 days (Jul 17, 2025)
Oct 7, 2020Oct 21, 2020-22.6%10 days44 days (Dec 23, 2020)
Jul 9, 2026Sep 16, 2026-14.7%48 daysNot yet recovered
Apr 27, 2026May 19, 2026-14.1%16 days14 days (Jun 9, 2026)
Nov 10, 2025Feb 12, 2026-13.2%64 days17 days (Mar 10, 2026)

Declines of 10% or more from a closing high, measured on daily closes.

Financial statements

Market cap
$6.07B
P/E (TTM)
32.8
EPS, diluted (TTM)
$9.35
Revenue (TTM)
$290.5M
52-week range
$175.89 – $326.63
FY 2021FY 2022FY 2023FY 2024FY 2025
Revenue$241.5M$196.2M$131.3M$167.1M$268.1M
Gross profit$179.4M$143.4M$96.3M$156.1M$261.5M
Operating income$103.9M$3.0M$11.9M-$22.6M$47.2M
Net income$57.1M-$33.4M$52.2M-$4.0M$124.5M
EPS (diluted)$3.34-$1.98$2.94-$0.22$6.13
Q3 2024Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026
Revenue$51.8M$42.8M$45.3M$47.6M$115.5M$59.7M$51.7M$63.7M
Net income-$7.2M-$31.1M-$42.5M$4.8M$117.3M$44.8M-$13.3M$48.5M
EPS (diluted)-$0.39-$1.64-$2.21$0.24$5.68$2.12-$0.67$2.22
FY 2021FY 2022FY 2023FY 2024FY 2025
Operating cash flow$78.8M$137.8M$49.6M$97.0M$49.4M
Capital expenditure-$8.8M-$17.9M-$53.8M-$19.6M-$452,000
Free cash flow$70.0M$119.9M-$4.3M$77.4M$48.9M
Dividends paid$0$0$0$0$0
Net share buybacks$15.3M$3.2M$22.4M$37.1M$99.9M

Cash outflows are shown as negative numbers.

Cash and short-term investments
$1.36B
Total assets
$2.19B
Total liabilities
$1.22B
Total debt
$1.13B
Net debt
$124.8M
Shareholders’ equity
$967.5M

As of Jun 30, 2026 (filed Aug 7, 2026).

Dividends

Ex-dateAmountPaid
Jul 2, 2010$0.12—
Apr 3, 2007$2.50Apr 19, 2007

Short interest

Shares sold short
2,632,434
Days to cover
13.53
Change vs previous report
+6.1%

FINRA short interest, settlement date Sep 15, 2026.

Stock splits

Nov 2, 2022
1,603-for-1,000
Nov 19, 2010
1-for-6