Stocks · Healthcare · Biotechnology

Arrowhead Pharmaceuticals, Inc. ARWR

$62.35 -2.87% Close, Oct 5, 2026 · NASDAQ · Market cap $9.04B

Strong growthHigh quality

Next earnings report: Nov 24, 2026

Scroll or pinch to zoom, drag to move. Daily prices adjusted for splits. Markers: E = earnings (green beat, red miss), S = split, D = dividend.

Three things to know

  1. Operating margin narrowed to -33.8% from -18.8% a year earlier.
  2. Over the past year the stock returned +80.2%, ahead of the S&P 500 by 64.4 percentage points.
  3. Revenue over the last four quarters was $669.5M, up 16.8% from a year earlier, accelerating from 14.1% a quarter earlier.

PromtFinance scores

Each score is a percentile within the Healthcare sector (0–100). Under each score: how the stock ranks in its sector on every component. As of Oct 6, 2026.

Growth89Strong

How fast revenue, earnings and cash flow are growing.

  • Revenue growth (TTM, YoY)Top 36%
  • Revenue growth, 3-year CAGRTop 14%
  • Revenue growth accelerationTop 24%
Quality84Strong

Returns on capital, margins, earnings quality and balance-sheet strength.

  • Return on invested capitalTop 44%
  • Gross marginTop 2%
  • Operating marginBottom 39%
  • Accruals (lower is better)Top 28%
  • Interest coverBottom 48%
Value53Neutral

How cheap the shares are relative to earnings, cash flow and their own history.

  • Earnings yieldTop 40%
  • Free-cash-flow yieldTop 38%
  • EBITDA / enterprise valueTop 41%
  • Sales / enterprise valueBottom 25%
Momentum59Neutral

Strength and persistence of the price trend, including versus the S&P 500.

  • 12-month return excluding last monthTop 10%
  • 6-month returnBottom 44%
  • 1-year return vs S&P 500Top 20%
  • Distance from 52-week highBottom 47%
  • Trend checklist (0–4)Bottom 36%
Revisions11Very weak

Earnings surprises and analyst sentiment (estimate-revision history is being collected).

  • Average EPS surprise, last 4 quartersBottom 17%
  • Consecutive EPS beatsBottom 20%
  • Share of analysts rating BuyBottom 42%
  • Upside to consensus price targetTop 49%
Stability24Very weak

Low volatility, shallow drawdowns, low market sensitivity and modest leverage.

  • Volatility, 60 days (lower is better)Bottom 42%
  • Maximum drawdown, 3 yearsBottom 43%
  • Beta vs S&P 500 (lower is better)Bottom 6%

What changed

Latest four quarters versus the same period a year earlier (growth: versus one quarter earlier).

MeasureBeforeNow
Revenue growth (YoY)14.1%16.8%↑
Gross margin99.1%100.0%↑
Operating margin-18.8%-33.8%↓
FCF margin-3.1%-11.2%↓

Fundamental momentum

MeasureNow (TTM)Year / quarter beforeSector rank
Revenue growth (TTM, YoY)16.8%14.1%↑Top 36%
Gross margin100.0%99.1%↑Top 2%
Operating margin-33.8%-18.8%↓Bottom 39%
Net margin-47.8%-25.9%↓—
Free-cash-flow margin-11.2%-3.1%↓—
Return on invested capital-12.1%—Top 44%
Revenue growth, 3-year CAGR50.5%—Top 14%

Quality of earnings and balance sheet

Accruals (net income − OCF) / assetsLower is better; high accruals can signal weaker earnings quality.
-12.4%
Stock-based compensation / revenueA cost to shareholders through dilution.
10.5%
Receivables growth vs revenue growthReceivables growing much faster than sales can be a warning.
-28.6 pp
Interest cover (operating income / interest)How many times operating profit covers interest.
-2.4×

Shareholder returns

Dividend yield (dividends paid, TTM)
0.00%
Net buyback yield (TTM)
-3.36%
Shareholder yield
-3.36%
Share count change, 1 year
+3.1%
Share count change, 3-year CAGR
+10.2%

Shareholder yield = dividends + net buybacks over the last four quarters, divided by market cap.

Based on the four quarters through Jun 30, 2026 (filed Aug 4, 2026).

Earnings and expectations

Earnings momentum

Consecutive EPS beats
0
Beats in the last 8 reports
2 of 8
Average EPS surprise, last 4
-29.1%
Average 2-day reaction, last 8
+2.4%
Positive 20 days after report
4 of 8

Analysts

Consensus price target
$100.63
Target vs current price
+61.4%
Analysts with a rating
22
Share rating Buy or Strong Buy
73%
Consensus rating
Buy

How the stock reacted to recent reports

Report dateEPS surprise2 days5 days20 days60 days
Aug 4, 2026-6.3%+4.2%+2.7%-4.2%—
May 7, 2026+14.7%-1.5%-1.6%-5.0%+8.7%
Feb 5, 2026-63.3%-5.0%-9.6%-6.6%+9.9%
Nov 25, 2025-61.3%+5.7%+30.9%+57.8%+42.7%
Aug 7, 2025-34.0%-1.5%+22.6%+71.7%+159.4%
May 12, 2025+4683.3%+7.2%+20.6%+27.2%+25.2%
Feb 10, 2025-231.0%-1.6%-1.4%-24.9%-35.4%
Nov 26, 2024-31.4%+12.0%+38.7%+4.5%+3.9%

Returns from the close before each report. Past reactions do not determine future ones.

Earnings history

Report dateEPSEstimateSurpriseRevenue
Aug 4, 2026-$1.36-$1.28-6.3%$75.3M
May 7, 2026-$0.93-$1.09+14.7%$73.7M
Feb 5, 2026$0.22$0.60-63.3%$264.0M
Nov 25, 2025-$0.18-$0.11-61.3%$256.5M
Aug 7, 2025-$1.26-$0.94-34.0%$27.8M
May 12, 2025$2.75-$0.06+4683.3%$542.7M
Feb 10, 2025-$1.39-$0.42-231.0%$2.5M
Nov 26, 2024-$1.38-$1.05-31.4%$3.6M

Valuation in context

MultipleNow5-year median5-year percentileSector rank (cheapness)
EV / Sales14.71×——Bottom 25%
Free-cash-flow yield-0.83%——Top 38%
Earnings yield-3.59%——Top 40%

Technical state

Trend checklist

  • ✗ Price above 20-day average
  • ✗ Price above 50-day average
  • ✗ Price above 200-day average
  • ✓ 50-day average above 200-day
  • ✗ MACD histogram positive

Trend quality

Days above the 50-day average
0
Days above the 200-day average
0
50-day average slope (20 days)
-4.4%
200-day average slope (20 days)
+1.9%
Distance from 50-day average
-22.4%
Distance from 200-day average
-14.0%
RSI (14)
27.8
Relative volume
0.96×

Risk and drawdowns

Volatility, 60 days (annualized)
59.8%
Volatility vs own 5-year history
44th percentile · Normal for this stock
Beta vs S&P 500 (2 years, weekly)
2.48
Correlation with S&P 500
0.53
Current drawdown from 1-year high
-30.4%
Maximum drawdown, 3 years
-74.7%

Largest declines in the past six years

From peakTo lowDeclineLengthRecovery
Feb 5, 2021Apr 8, 2025-89.0%1047 daysNot yet recovered
Nov 17, 2020Nov 25, 2020-19.4%6 days10 days (Dec 10, 2020)
Dec 23, 2020Jan 5, 2021-14.9%7 days22 days (Feb 5, 2021)

Declines of 10% or more from a closing high, measured on daily closes.

Financial statements

Market cap
$9.04B
EPS, diluted (TTM)
-$2.24
Revenue (TTM)
$669.5M
52-week range
$34.61 – $95.49
FY 2021FY 2022FY 2023FY 2024FY 2025
Revenue$138.3M$243.2M$240.7M$3.6M$829.4M
Gross profit$138.3M$232.8M$228.2M-$15.0M$829.4M
Operating income-$149.0M-$178.5M-$205.0M-$601.1M$98.3M
Net income-$140.8M-$176.1M-$205.3M-$599.5M-$1.6M
EPS (diluted)-$1.36-$1.67-$1.92-$5.00-$0.01
Q4 2024Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026Q2 2026Q3 2026
Revenue$0$2.5M$542.7M$27.8M$256.5M$264.0M$73.7M$75.3M
Net income-$170.5M-$173.1M$370.4M-$175.2M-$23.8M$30.8M-$132.7M-$194.3M
EPS (diluted)-$1.40-$1.39$2.75-$1.26-$0.17$0.22-$0.93-$1.36
FY 2021FY 2022FY 2023FY 2024FY 2025
Operating cash flow$171.3M-$136.1M-$153.9M-$462.9M$179.6M
Capital expenditure-$23.6M-$52.8M-$176.7M-$141.5M-$22.7M
Free cash flow$147.7M-$188.9M-$330.6M-$604.3M$156.9M
Dividends paid$0$0$0$0$0
Net share buybacks$0$5.2M$3.1M$431.7M$270.4M

Cash outflows are shown as negative numbers.

Cash and short-term investments
$1.60B
Total assets
$2.11B
Total liabilities
$1.65B
Total debt
$864.1M
Net debt
$809.3M
Shareholders’ equity
$465.5M

As of Jun 30, 2026 (filed Aug 4, 2026).

Short interest

Shares sold short
9,272,290
Days to cover
5.15
Change vs previous report
-1.6%

FINRA short interest, settlement date Sep 15, 2026.

Stock splits

Nov 17, 2011
1-for-10
Jan 15, 2004
1-for-65